12 results
The primary objective of this study is to assess whether motor learning using external attentional focus instructions results in superior single-task motor performance, movement automaticity, and dual-task performance in inpatient stroke patients…
To evaluate the effects of tDCS on information processing speed in comparison to sham tDCS in patients after stroke with ascertained reduced processing speed. A proof of principle study.
1) Is e-COGRAT usable within the ABI population?2) What are the patients* experiences with e-COGRAT?3) What are the therapists* experiences with e-COGRAT?4) What changes in the e-COGRAT are necessary?5) Does this pilot with e-COGRAT show a decline…
The main objective of this study is to find (epi)genetic markers including SNPs/haplotypes, DNA methylation and RNA expression correlating with cognitive decline in clinical patients with Mild Cognitive Impairment (MCI) and Subjective Cognitive…
The current study is part of a larger project that aims at identifying genetic profiles that render subject vulnerable to pronounced memory decline at old age. This part of the project will assess cognitive functions in three different age cohorts…
Previous studies have suggested an association between FD and cognitive impairment but these were flawed either by lack of power, used variable assessment of cognitive functioning and/or merged results of different phenotypes and sexes. It is of…
The general objective of this study is to gain more understanding of motor and cognitive impairment and the way these two are linked after stroke. There are two more specific objectives: exploring (1) the link between motor and cognitive impairment…
The main objectives are to understand how clinical markers and biomarkers previously identified in younger and older AD cohorts apply to the extreme elderly (90+ years old) and to identify novel biomarkers linked with resilience to developing…
Primary objectives: * To demonstrate the effects of CAD106 and CNP520, respectively, vs. placebo on Time-to-event (TTE), with event defined as a diagnosis of MCI due to AD or dementia due to AD, whichever occurs first during the course of the study…
Our objective is to get insight into whether and how the visual system reorganises after acquiring HH. Visual processing will be investigated and cortical reorganisation at a structural level will be examined. For this purpose, we will assess…
This study aims to investigate the retina, macula and optic nerve head with Optical Coherence Tomography (OCT) in a cohort of AD patients in order to identify a neurodegenerative signature of AD consisting of neuroretinal degeneration, vascular…
Primary objectivesPart 1To evaluate the single dose safety and tolerability of donepezil 10 mg when administered with placebo, glycopyrrolate or trospiumPart 2To evaluate the safety and tolerability of donepezil when given with concomitant placebo,…