341 results
To investigate whether deep and slow breathing exercises can reduce pain induced by mobilizing from bed to chair after major abdominal surgery, compared to a reading task.
The purpose of the study is to investigate to what extent FE 201836 is tolerated. It will also be investigated how quickly and to what extent FE 201836 is absorbed and eliminated from the body (this is called pharmacokinetics). Also the effect on…
This study aims at, first, assessing the most relevant exposure aspects of night-shift work and, second, identifying biomarkers for both acute and chronic circadian disruption associated to these specific nightshift work aspects. By applying…
Primary objective: To assess the impact of a low glycaemic load (GL) diet as compared to a *Western* diet on metabolic flexibility (the change in RQ) upon a hyperinsulinemic euglycemic clamp. Secondary objectives: 1) To assess the impact of low GL…
To assess the effectiveness and patient perception of benefit of the ReVENT Sleep Apnea System in patients diagnosed with Obstructive Sleep Apnea due to primary tongue base closure.
Primary objective:To determine the response to a 144-hour (6 day) continuous intravenous infusion of SAGE-547 compared to placebo administered to support the weaning of all third-line agents in subjects with SRSE, and for the response to endure at…
The objective of the study is to determine the protein profile of cerebrospinal fluid of non-pregnant women using mass-spectrometry.This study is a follow-up project on the previously performed study (LEPRA, CSF and pre-eclampsia, MEC 2007-087). In…
The objective of this study is to develop, test and evaluate a psychosocial intervention for dialysis patients aimed at better coping with, and reducing fatigue (primary outcome) and thus improving the quality of life (secondary outcome).
Primary Objective- To explore the effects of NeoRecormon on well-trained cyclists and their cycling performance by exercise parameters. Secondary Objectives- To explore the effects of NeoRecormon on well-trained cyclists and their cycling…
This study aims to clarify whether the brain dopamine and noradrenaline system underlie the electrocortical responses (event-related potentials) that are sensitive to cues signalling reward and probability, the P200 and P300.
To determine the effects, feasibility and costs of a multi-component cognitive behavioural intervention for reducing fear of falling and associated activity restriction in hip fracture patients admitted for geriatric rehabilitation.
The primary study objective is to evaluate the psychophysiological effects of a psychological expectancy training directed at optimizing immune function compared to a control group in healthy male subjects.
The objective of this study is to investigate the effect of incongruent and congruent visual feedback on pain reports and Pressure Pain Thresholds (PPTs).
Primary Objective: To objectively and subjectively investigate sleep and fatigue among Dutch and British offshore workers and their influence on health safety and performance.Secondary Objective(s): • To examine the course of cortisol, cotison and…
The aim of our pilot intervention study is 1) to describe the effects of lactic acid-containing vaginal douching on the vaginal microbiota dynamics using novel molecular laboratory methods.2) to describe the effect of lactic acid-containing vaginal…
The primary objective is to determine the effects of dietary nitrate (beet root juice) on the microcirculatory profile in healthy adults. The secondary objectives are 1) to determine the effects of dietary nitrate on macrocirculatory parameters, 2)…
In the current study we will investigate the effect of non-pharmacological treatment on postoperative acute pain and PONV in patients undergoing a laparoscopic cholecystectomy. Patients will receive on the recovery an ice-lolly, chewing gum or no…
Objective of the INFINITE 2 MRI Study is to collect data on the ImageReady* MR Conditional Pacing System in subjects already implanted with the system according to standard medical guidelines for PM implantation and meets the labeled MRI Conditions…
Collection of skin tissue and blood samples from patients with mild to moderate psoriasis for efficacy testing of a new compound in a humanized mouse model.
The primary objective of this study is to explore user acceptance of the ironHand (iH) system by elderly. Secondary objectives are to examine the direct effect on functional task performance, changes in hand strength and movement execution of such a…