89 results
To compare acylated and unacylated ghrelin concentrations in pregnant women with GD and without GD.
In this prospective study we aim to find out whether an early refeeding strategy in addition to standard care can improve maternal and neonatal outcome and reduce hospital stay.
The objective of the study is to determine the protein profile of cerebrospinal fluid of non-pregnant women using mass-spectrometry.This study is a follow-up project on the previously performed study (LEPRA, CSF and pre-eclampsia, MEC 2007-087). In…
To validate spectral analysis of the fHRV as a new method for fetal monitoring. To determine the exact influence on fHRV of several commonly used medicines in obstetric care; namely tocolytic drugs, corticosteroids, antihypertensive agents,…
1a. Determine whether the effect of low-molecular-weight heparin can be explained by aspirin resistance. 1b. Assess the consistency of aspirin resistance during and after pregnancy measured with several complementary devices. 2. Determine…
The aim of this study is to investigate the effect of guided tapering in early pregnancy as compared to continuation of SSRIs during pregnancy. We will study effects on both mother and child with a pragmatic approach.
a. To investigate the phenotype and function of immunological cells present in endometrial and peripheral blood of women with a history of recurrent miscarriages and women without any known pregnancy complications.b. To investigate the association…
In the present proposal, we aim to assess the cost-effectiveness of the use of CGMS in diabetic pregnancies.
The striking difference in uptake of Down*s Syndrome screening between countries that otherwise show close resemblance, particularly regarding healthcare policy, social and cultural factors (including non-directiveness of counselling, autonomous and…
The main goal of this study is to establish the reliability (internal consistency and interrater reliability) and validity (discriminant, contruct and predictive validity) of the INCAS. Differences between the SMI and healthy group will be studied (…
The prime objective of the IMPROvED project is to develop a clinically robust predictive blood test for pre-eclampsia, using innovative technologies and utilising novel metabolite and protein biomarkers. This blood test is targeted to all first time…
The overall aim of the DALI study is to identify the best available measures to prevent GDM in an ongoing pregnancy, to provide a cost-benefit calculation of GDM prevention for health care systems, and to establish a pan-European cohort of mother-…
To investigate the hypothesis that temporising treatment of women with early-onset, severe preeclampsia improves infant outcome and may reduce direct treatment costs in comparison to short-term planned delivery, while persistent maternal morbidity…
Primary objectives:To determine the difference in effect of prophylactic daily LMWH injections with standard high risk antenatal care compared to standard high risk antenatal care only for the prevention of preeclampsia and IUGR and to assess the…
The overall aim of the DALI study is to identify the best available measures to prevent GDM in an ongoing pregnancy, to provide a cost-benefit calculation of GDM prevention for health care systems, and to establish a pan-European cohort of mother-…
The principal aim of this study is to elucidate the role of the glycocalyx in the pathogenesis of pre-eclampsia by assessing: - Whether the glycocalyx is affected in pre-eclampsia and is related to its severity.- Whether glycocalyx perturbation is…
To test The Selection Failure hypothesis by assessing A) the degree of embryo invasiveness and decidual acceptance (the quality of decidualization, endometrium-embryo communication and endometrial stromal cell (ESC) migration) and B) the angiogeneic…
This study aims to test whether non-invasive measures of SNS activity can predict preeclampsia and whether magnesium sulphate in preeclamptic patients reduces the hypersympathetic state. We will quantify SNS activity using the pre-ejection period (…
Applicability of fetal brain imaging techniques for clinical purposes.
For pregnant women with non-severe non-proteinuric maternal hypertension at 14-33 weeks, will *less tight* control (target dBP of 100mmHg) vs. *tight* control (target dBP of 85mmHg) increase or decrease the likelihood of pregnancy loss or neonatal…