237 results
The purpose of the study is to identify genetic changes that cause gender dysphoria.
• To determine the immunogenicity prediction in PBMCs of patients treated with Infliximab and Adalimumab using the MAPPs assay.• To investigate whether the peptides presented upon in vitro loading of Dendritic Cells are also presented in vivo after…
The primary objective of this study is:- To determine the potential difference in MT and RNFLT between treated and untreated patients with anisometropic or strabismic amblyopia. Secondary objectives are:- To determine the potential differences in MT…
The main objective of this study is to collect DNA within the frame of an existent study to bring together detailed, longitudinal data about adolescents* risk behaviors and peer relationship networks with information on genetic markers. Proposed…
1. To study the mechanisms that control endothelial and platelet secretion using blood outgrowth endothelial cells (BOECs) as an ex vivo model of endothelial and platelet secretion, in order to identify new regulators of and further unravel their…
To gain more insights in the mechanical properties of soft tissue under high risk for deep tissue injury type of pressure ulcers with US and MR Elastography.
The primary objective of this study is to develop an objective, patient-friendly assessment setup with which relevant characteristics of movement disorders of the head, such as CD, can be obtained from video- and depth-images (obtained using…
The first aim of this study is to examine differences in implicit and explicit learning in children born very preterm. The second aim is to test the alleged role of working memory and attention on (explicit) motor skill learning in preterm children…
The primary objective is to investigate quality of life after switch to a combination therapy including boosted DRV and DTG. Secondary objectives are to investigate 1) the residual viral replication, 2) level of virus production from infected cells…
Primary objective: To identify specific bacteria or a characteristic bacterial composition in the oral and gut microbiome of pSS patients compared to non-Sjögren*s syndrome sicca (non-SS sicca) patients, SLE patients and healthy controls.Secondary…
This project consists of two related studies. The objective of part 1 is to investigate the effect of elevated plasma lactate levels that are sufficient to impair awareness of hypoglycemia on brain lactate concentrations during euglycemia and…
To assess the change in excitability parameters induced by IVIG infusion. This will be achieved by comparing excitability-parameters between the time of maximal weakness (just before the next IVIG infusion) and the time of maximal clinical…
Primary objective is to quantitatively assess differences in in vivo neuroinflammation in patients before and after coronary artery bypass grafting (CABG) surgery. Secondary objective is to study whether diffferences in in vivo neuroinflammation are…
We hypothesize that PD patients with and without tremor have different patterns of midbrain structural integrity in (dopaminergic) nuclei, different patterns of functional connectivity from midbrain to basal ganglia, differences in GABA-ergic tone…
Primary objective:To determine the incidence of Clostridium difficile infection (CDI) in hospitalized patients aged * 50 years old and receiving oral or intravenous fluoroquinolones, cephalosporins, penicillins + beta-lactamase inhibitors,…
The primary endpoint will be descriptive histology on placental bed biopsies and placenta in healthy pregnant women or women with preeclampsia and/or IUGR in need of caesarean section. In particular, the study will aim to find the degree of…
To increase insight in cerebral injury of perinatally HIV-infected children by comparing neurological, ophtalmological and neurocognitive outcomes to those of matched controls (with respect to age, sex, ethnic background, home environment and socio-…
Nasal mucus proteins have different origins and production sites and gene expression does not necessarily result in functional metabolites. The aim of this proposed project is to try and analyze in a holistic proteomic approach the response to…
Little is currently known about the importance of individual intrinsic and extrinsic factors on sleep in the ICU. This study will investigate the role of sound, light and the inherent experience of the ICU environment on the incidence of arousals,…
Investigate whether restoration of intestinal butyratelevels improves the intestinal barrier function and decreases the inflammatory status in CKD patients.