511 results
To evaluate the effects of short term supplementation of Phe to levels comparable to levels observed in adult patients who fully discontinued their diet on neuropsychological functions and wellbeing of adult patients with PKU.
PrimaryTo determine the hematological response (complete response(CR) / partial response (PR)) rate as per Bladé criteria to treatment with oral LBH589 of patients with MM who have received at least two prior lines of therapy and whose disease is…
The objective of this trial is to explore the efficacy, safety, tolerability, pharmacokinetics, and pharmacokinetic-pharmacodynamic relationships of telaprevir when administered as 750 mg q8h or 1125 mg q12h in combination with Peg IFN alfa2a (…
To determine the rate of transmission of prilocaine across the placentaTo determine the levels of methemoglobinemia in newborns after perineal block with prilocaine during labor (following the regimen used in our hospital)To determine the levels of…
We hypothesize that NK and/or T cell-mediated immunotherapy may represent a novel therapeutic option for patients with refractory and/or metastatic OS. Therefore, we will study molecular mechanisms that determine the susceptibility of osteosarcomas…
To explore the influence of psychological factors - e.g. causal attribution, religiosity, mindfulness, Type D personality, benefit finding, and optimism - on survival, fatigue, depression, and health-related quality of life of stage IIIb/IV…
The objective of this study is to examine the feasibility of developing a useful and transferable treatment protocol and to study the impeding and facilitating factors of the implementation of the intervention in a fieldsetting. The effects of the…
The objective of this study is to develop an effective behavioural treatment for severe drooling. The hypotheses are:1. A behavioural program containing instruction, goal setting, positive practice, self-management techniques, and positive and…
The purpose of this study is to monitor whether preicncisional bupivacaine (bupivacaïne 0,5% with epinefrine 1:200.000), infiltration in trocarcincisions reduces postoperative wound pain in patients undergoing laparoscopic cholecystectomy.
Main objective of this study is to assess the effects of MVD versus RF of the pterygopalatine ganglion in management of patients with persistent, drug-resistant SN in terms of pain reduction and improvement of quality of life.
The objective of this study is determine the functional outcome in daily life of adults with obstetric brachial plexus injury and determine which limitations in daily life they encounter, functional as well as psychological and social.
The study objective is the assessment of influence on glucose homeostasis as a consequence of starting switching, discontinuing or doses changes with antidepressants in a population of diabetic patients.
To asses the clinical effect of low dose pipamperone on cognitive functions of elderly patients suffering from cognitive dysfunction.
Up to now there are only very limited data from clinical studies available comparing treatment of mandibular class II furcation defects with various types of particulate graft materials in combination with GTR to the treatment with such a graft…
This study aims to investigate the reaction of the peri-implant tissues to these materials when used in oral implant dentistry.
The objectives of this study are as follows:Primary Efficacy Objective:• To assess the effect of PG-760564 on the proportion of patients meeting the American College of Rheumatology 20 response criteria (ACR 20) at 12 weeks;11Secondary Efficacy…
"the effects of elastic stockings after varicose vein surgery".
The primary objective of this study is to assess the efficacyand safety of modifications of the laser treatment to increase the clearance of port wine stains.
Objective is to study the effect of Targeted Training Therapy on balance control in children with Cerebral Palsy.
1. To compare the effectivity of TVT-O and TVT-S as surgical correction of stress-incontinence. 2. To compare the complications of TVT-O and TVT-S.3. To compare the morbidity and post-operative recovery of TVT-O and TVT-S. 4. To compare the…