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ID
Source
Brief title
Health condition
Alveolitis
Sponsors and support
Intervention
Outcome measures
Primary outcome
NRS
Secondary outcome
• Does rinsing postoperative with chlorhexidine lower the postoperative complications, after surgical removal of impacted lower third molars?
• Does rinsing postoperative with chlorhexidine lower the need for analgesics postoperative?
• Does rinsing postoperative with chlorhexidine reduces the number of out-patient contacts?
• Does rinsing postoperative with chlorhexidine reduces / affect the number of days of leave from work or study?
Background summary
Background of the study:
One of the most common postoperative complications after the removal of a third molar is a condition known as dry socket. This term has been in use since 1896. Since then several other terms have been used, including alveolar osteitis, postoperative alveolitis, alveolitis, sicca dolorosa and fibriniolytic alveolitis. Bim labelled the complication fibrinolytic alveolitis which is the most accurate of the terms, but also the least used. The condition has generally been characterised by delayed healing associated with degradadtion of clot, and is usually accompanied by persistent, radiating, pain postoperativively in and around the extraction site that is not easily relieved by analgesics6.
Because of the pain, swelling and trismus, patients also tend to have a greater need for painkillers. If it is possible to reduce the amount and severity of postoperative pain felt by patients the postoperative period would be more endurable, the quality of life will be less affected, and in addition to this it is possible that the amount of analgesics taken by patients after surgery could be lowered7. It can be a burden for both patients an surgeons and my result in a loss of productivity because at least 45% of patients require multiple visits to the surgeon.
Objective of the study:
Many authors have advocated different methods of treating alveolar osteitis. One of these is the use of 0,12% chlorhexidine before and after the removal of the third molar. Despite many years of research, however, little progress has been made and so a study with large enough sample and standard outcome measures is warranted.Goal of this study is assess the effect of postoperative use of chlorhexidine on postoperative complaints after surgical removal of a lower third molar.
Study objective
Rinsing will reduces NRS score
Study design
Primary outcome: during the recall visit one week after the surgery the diary with the NRS score is collected. The highest NRS score and the mean NRS score is noted. Data is noted in online in the Research Manager database.
Secondary outcomes: at the day of the surgery the oral hygiene, smoking, infection of the operculum en pockets are noted as parameters in the Research Manager database. At the recall visit 7-days after surgery Bleeding, Dehiscense, Foodimpaction, Alveolitis, Fever, Painkiller use, Days from work and unplanned visits are noted. Data is noted in online in the Research Manager database.
Intervention
Chlorhexidine
Inclusion criteria
In order to be eligible to participate in this study, a subject must meet all of the following criteria: patients over 18 years of age (non smoking) referred for removal of a wisdom tooth in the mandible. Patient has ASA I.
Exclusion criteria
- Patient is younger than 18 years
- Patient has an ASA of II,III en IV
- Patient has only one maxillary third molar that needs to be extracted/removed
- Patient has an active pericoronitis
- In case of planned coronectomy
- Patient has trismus
- Patient has chronic pain
- Patient is pregnant
- Patient has a known allergy for ibuprofen of other NSAID’s
- Patient has a known allergy for articaine of epinefrine
- Intra-operative compilations for example excessive bleeding
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL9761 |
| CCMO | NL71727.075.20 |
| OMON | NL-OMON54943 |