The main objective of this study is to explore the correlation between the patient*s perception of the injury, clinical tests and parameters found using DTI and MRI during the rehabilitation process.
ID
Source
Brief title
Condition
- Muscle disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main endpoints of this study are:
DTI derived parameters and characterization of changes in of affected muscles,
in the course of a hamstring injury and their correlation with self-reports and
clinical assessments.
Secondary outcome
MRI T1 and T2 images shall be scored by a radiologist using a standardized
form. The questionnaires regarding patient self-reports concerning injury
severity will consist of several questions, taking a couple of minutes to fill
in. Clinical assessments will be conducted by the (medical) physicians of AFC
AJAX and will be scored accordingly on a standardized form. Active range of
knee motion (AROM) and knee extension (with hip at 90 degree angle) will be
measured in degrees. Pain experienced during stretch, eccentric and concentric
resistance will be documented using VAS pain scores (1-10).
Background summary
Injuries are a frequent occurrence among professional football players. As the
aforementioned trauma is known for its high prevalence of recurrence, it begs
the question whether there is an overall premature *return-to-play*. Especially
as regeneration and remodeling may occur up to 9 months following the injury 1.
In addition, studies regarding potential prognostic markers predicting *return
to play* following the said injury are scarce.
In light of the current medical literature, efficiently predicting the
convalescent period of an athlete remains difficult. Our interest lies in
particular with acute hamstring injuries occurring during sudden explosive
movements (such as jumping, shooting, twisting, turning and change of
direction), sprinting or high intensity running.
Diffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging (MRI) technique
that is able to characterize muscle and nerve fiber architecture as well as to
provide insights in local histopathological status of nerve and muscle tissue 2*
6.
The main research question of this explorative study is:
What is the association between the patient*s perception of the severity of the
injury, clinical tests and parameters found using DTI and MRI during the
rehabilitation process.
We hypothesize that the DTI findings will provide insights regarding muscle
repair and the convalescent period, which will not entirely correlate with
current used patient self-perception and clinical tests. Thus return-to-play
will not concur with complete normalization of DTI and MRI parameters.
Study objective
The main objective of this study is to explore the correlation between the
patient*s perception of the injury, clinical tests and parameters found using
DTI and MRI during the rehabilitation process.
Study design
Observational prospective study
Study burden and risks
Patients have no benefit by participating in this study.
Risks for the subjects undergoing a MRI examination are minimal, provided
precautions have been made to prevent examining individuals with
contraindications. For this purpose, the routine MRI contra indications form of
the AMC will be used. Findings in this study will not be used for management. A
group-related benefit of this diagnostic study is that DTI potentially has
clinical utility in the assessment of therapeutic intervention if proven a
suitable method to illustrate and predict the convalescent period. This is now
based on hypothetically less reproducible strength measurements.
Meibergdreef 9
Amsterdam 110DD
NL
Meibergdreef 9
Amsterdam 110DD
NL
Listed location countries
Age
Inclusion criteria
*hamstring tear and positive MRI (O*Donoghue grade 1-2) 7 will be recruited through the sports physician of AFC Ajax Amsterdam.
* Diagnosis has to fulfill the UEFA acute hamstring tear criteria (Appendix 1)
* Tear has to be the result of explosive movements such as, sprinting or high intensity running.
Exclusion criteria
* Complete ruptures to the HMC will be excluded due to their different course of recovery.
recurrent tear
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL48190.018.14 |