We aim to investigate in a pilot study the blood platelet mRNA profiles in patients with IIM and a known malignancy.
ID
Source
Brief title
Condition
- Miscellaneous and site unspecified neoplasms malignant and unspecified
- Neuromuscular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
blood platelet mRNA profile
Secondary outcome
na
Background summary
The screening for malignancies in patients with myositis may be improved and
less invasive by novel techniques.
Study objective
We aim to investigate in a pilot study the blood platelet mRNA profiles in
patients with IIM and a known malignancy.
Study design
Pilot study - cross sectional cohort study in ten patients
Study burden and risks
The overall risk of this study is considered low and relate to two extra tubes
during a single episode of blood sampling which is part of clinical care.
Potential benefits include an improvement of cancer screening methods for
patients with myositis.
Meibergdreef 9
Amsterdam 1105AZ
NL
Meibergdreef 9
Amsterdam 1105AZ
NL
Listed location countries
Age
Inclusion criteria
1. Patients with dermatomyositis (DM) and immune mediated necrotizing myopathy
(IMNM) with or without a myositis specific antibody, with a known malignancy
(out of a list of 16 malignancies).
2. Informed consent.
Exclusion criteria
No informed consent
Women who are pregnant or breastfeeding
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL78849.018.21 |