No registrations found.
ID
Source
Brief title
Health condition
gele koorts, oudere, reizen, neutraliserende antistoffen, bijwerkingen
yellow fever, elderly, travel, neutralizing antibodies, adverse events
Sponsors and support
Intervention
Outcome measures
Primary outcome
1. Neutralizing antibodies;
2. Yellow fever viremia
Secondary outcome
1. Presence of yellow fever virus proteins in urine samples,
2. adverse events
Background summary
Comparison of neutralizing antibodies and viremia induced by yellow fever vaccination between elderly travellers en younger controls. Adverse events following yellow fever vaccination will be monitored.
Study objective
The induction of immunity might be slower in older persons than in younger individuals. This could influence the occurence of adverse events induced by the vaccine.
Intervention
Yellow fever vaccination (only an extra intervention in control group), blood drawing and urine sampling
P.O. Box 9600
A.H.E. Roukens
Albinusdreef 2
Leiden 2300 RC
The Netherlands
a.h.e.roukens@lumc.nl
P.O. Box 9600
A.H.E. Roukens
Albinusdreef 2
Leiden 2300 RC
The Netherlands
a.h.e.roukens@lumc.nl
Inclusion criteria
Elderly group:
1. Age of 60yrs or older;
2. Indication for yellow fever vaccination according to Dutch travel guidelines
Control group: age under 60yrs
Exclusion criteria
1. Immune suppression due to disease or medication;
2. Pregnancy
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1011 |
| NTR-old | NTR1040 |
| Other | : LUMC |
| ISRCTN | ISRCTN42180653 |