No registrations found.
ID
Source
Health condition
Blood flow measurement with MRI in the large vessel around the heart (aorta and pulmonary artery) show a measurement error; a velocity offset in the data.
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary study outcome parameter is the velocity offset in cm/s at the location of the aorta or pulmonary artery.
Secondary outcome
- To describe the offset error over the systems included in the study
- To test whether the static phantom offset corrections are valid, the difference between the velocity at the thorax wall and the phantom be assessed.
- The validity of offset corrections using higher order fitting, and the LPC filter.
Study objective
To validate in vivo the velocity offset correction method as published by Walker PG et al. (JMRI 3, 521 1993) such that it can assure velocity offsets < 0.6 cm/s at the ascending aorta and pulmonary artery for 2D through-plane phase contrast MRI velocity measurements at different centers and for different vendors.
Study design
There will an analysis at the end of the inclusion periode, at about 1 year.
Intervention
Observational study.
Seperate phantom measurements will be obtained after an in vivo clinical MRI scan.
VU University Medical Center
P.O. Box 7057, 1007 MB Amsterdam, the Netherlands
M.B.M. Hofman
de Boelelaan 1117
Amsterdam
The Netherlands
+31-20-4444 593
mbm.hofman@vumc.nl
VU University Medical Center
P.O. Box 7057, 1007 MB Amsterdam, the Netherlands
M.B.M. Hofman
de Boelelaan 1117
Amsterdam
The Netherlands
+31-20-4444 593
mbm.hofman@vumc.nl
Inclusion criteria
- Informed consent
- Sinus rhythm at CMR examination
- 2D flow acquisitions by MRI at the aorta or pulmonary artery without spatial infolding artefacts.
- MRI acquisition on MRI system by Siemens: Magnetom Avanto, VB17 or newer 1.5 T systems such; for GE: Signa Excite (HDx 15M4) or newer as the Optima MR360; and for Philips: Achieva R2.6.3 or newer as the Ingenia.
- MRI flow acquisitions with the general accepted standard settings
Exclusion criteria
- Incapacitated adults.
- Lack of a phantom measurement within the protocol specifications.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4720 |
| NTR-old | NTR4865 |
| Other | : None available |