No registrations found.
ID
Source
Brief title
Health condition
invasive hemodynamic monitoring has more complications compared to non invasive monitoring. However invasive monitoring is better compared to less invasive monitoring. Can less invasive monitroring devices be used during these procedure.
hemodynamic monitoring
SIRS
surgery
Sponsors and support
Afdeling anesthesiologie, pijn en palliatieve geneeskunde
postbus 9101
6500 HB NIJMEGEN
Intervention
Outcome measures
Primary outcome
Determining the reliability of the less invasive hemodynamic measurement methods with respect to the reference measuring method (= TPTD), for a variety of pre-defined moments peri and post OK.
Comparison absolute numbers; TPTD vs less invasive Cardiac Output (bias, precision, limits of agreement, percentage of error; Bland Altman plot). By time (T1 ... .T9), and all paired data points corrected for "repeated measurements".
Secondary outcome
ROC curve to detect SV change > 15%
Study objective
Non invasive hemodynamic monitoring is as good as invasive monitoring
Study design
T = 0, synchronization clocks, calibrate CCO PiCCO using TPTD,
T2 and T3 measurement in the middle of debulking period;
T4 start HIPEC;
T5 middle HIPEC;
T6 end HIPEC;
T7 end OK;
T8 and T9 on the IC around 6 and 12 hours post operative
Intervention
Comparison:
invasive hemodynamic monitoring (PICCO) vs less invasive monitoring (ProaQt and FloTrac) and non invasive monitoring (nexfin/clearsight)
Inclusion criteria
Patients undergoing a HIPEC procedure and receive hemodynamic monitoring with the TPTD through PiCCO monitoring.
Patients older than 18 years
Exclusion criteria
- Severe tricupid or aortic regurgitation
- Severe peripheral vascular dissease
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL5117 |
| NTR-old | NTR5249 |
| Other | CMO Regio Arnhem-Nijmegen : 2015-1793 |