No registrations found.
ID
Source
Brief title
Health condition
1. Pain;
2. nociceptive pain;
3. neuropathic pain.
Sponsors and support
Postbus 196
9700 AD Groningen
the Netherlands
Postbus 196
9700 AD Groningen
the Netherlands
Intervention
Outcome measures
Primary outcome
Safety and tolerability in healthy volunteers and patients: any self-reported experiences are recorded. Small neuropsychological tests are performed such as long number recollection and reverse recital of the months of the year.
Neuropathic pain model in healthy volunteers and neuropathic pain in patients: visual analogue scale of pain intensity.
Nociceptive pain model in healthy volunteers and patients: warmth detection threshold (oC) and heat pain threshold (oC).
Secondary outcome
During the pain studies (as opposed to the safety and tolerability studies where this is the main endpoint) all subjects are debriefed about whether any sensations were perceived during the experiment.
Background summary
N/A
Study objective
Low field TMS can reduce nociceptive and neuropathic pain.
Study design
Two lab visits, approx. one week apart.
Intervention
Transcraniele magnetische stimulatie met zwakke velden.
Inclusion criteria
1. 18-80 years old;
2. subjectively healthy;
3. neuropathic pain (patients only).
Exclusion criteria
1. Neurological (e.g. epilepsy) history (volunteers only);
2. Neurological history apart from neuropathic pain (patients only);
3. Psychiatric history;
4. Recent use (within four weeks) of antidepressants, antiepileptic drugs or prescription psychopharmaca;
5. Excessive use of: coffee (>10 units per day), alcohol (>10 units per day);
6. Recent use (within four weeks) of cannabis or any other non-prescription psychopharmaca;
7. Presence in the body of MRI incompatible implants, electronic implants (e.g. cardiac pacemakers),or connectors of electronic equipment (e.g. electrodes).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1060 |
| NTR-old | NTR1093 |
| Other | UMCG : microTMS001 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd |