No registrations found.
ID
Source
Health condition
cardiac surgery (hart chirurgie), thrombin generation (trombin vorming), coagulation (stolling)
Sponsors and support
Intervention
Outcome measures
Primary outcome
Whole blood thrombin generation results compared to automated plasma thrombin generation results
Secondary outcome
1. lab results (ROTEM, whole blood TG, classic coagulation tests)
2. clinical association with bleeding (amount of blood loss, fluid infusion and use of blood products)
Background summary
Post cardiac surgery patients may suffer from bleeding. For optimal tailoring hemostatic therapy thromboelastometry (ROTEM) is frequently used. Thrombin generation measurement could improve treatment. However this technique still is workintensive and time consuming. Whole blood thrombin generation might deliver the comparable results within a shorter period of time. It will be tested and compared to plasma thrombin generation, thromboelastometry and clinical parameters.
Study objective
Whole blood thrombin generation measurement is comparable to plasma thrombin generation in clinical setting.
Study design
measurement before and after surgery upon arrival on the ICU
Intervention
observational study investigating coagulation capacity by the means of whole blood thrombin generation.
MUMC+
P.Debeyelaan 25
M.D. Lancé
Maastricht 6202 AZ
The Netherlands
marcus.lance@mumc.nl
MUMC+
P.Debeyelaan 25
M.D. Lancé
Maastricht 6202 AZ
The Netherlands
marcus.lance@mumc.nl
Inclusion criteria
All consecutive patients after cardiac surgery during a period of 18 weeks.
Exclusion criteria
age under 18 yrs.
known coagulation disorder.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4091 |
| NTR-old | NTR4237 |
| Other | : METC-13-4-084 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |