No registrations found.
ID
Source
Brief title
Health condition
RSV lower respiratory tract disease (bronchiolitis or pneumonia).
Sponsors and support
Dr. M.C.J. Kneyber, paediatrician
Office 8 D 11
P.O. Box 7057
1007 MB Amsterdam
The Netherlands
Phone: 003120-4442413
Fax: 003120-4443045
e-mail: m.kneyber@vumc.nl
Intervention
Outcome measures
Primary outcome
Duration of hospitalisation.
Secondary outcome
1. Proportion and duration of oxygen therapy;
2. Proportion and duration of bronchodilator therapy;
3. Duration of tachypnoe (>40 breaths/min);
4. Duration of fever (> 37.5°C);
5. Duration of impaired feeding;
6. Number of infants referred to PICU
Course of RSV score.
Background summary
N/A
Study objective
Antibiotic treatment of hospitalised children with RSV LRTD has no beneficial effect on the clinical course.
Study design
N/A
Intervention
Azithromycine 10 mg/kg/day for three days versus placebo.
P.O. Box 7057
M.C.J. Kneyber
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4442413
m.kneyber@vumc.nl
P.O. Box 7057
M.C.J. Kneyber
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4442413
m.kneyber@vumc.nl
Inclusion criteria
Children <24 months of age with a virologically confirmed diagnosis of RSV lower respiratory tract disease, defined by a first episode of dyspnoea with increased body temperature (> 37.5° C), and/or cough, and/or coryza, and/or wheezing, and/or crackles on pulmonary auscultation.
Exclusion criteria
Age >24 months, children presenting with apnoea with signs of lower respiratory tract disease, nosocomial RSV infection, antibiotic treatment less than 7 days before hospital admission, abscence of informed consent by parents or legal representatives.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL111 |
| NTR-old | NTR142 |
| Other | : N/A |
| ISRCTN | ISRCTN86554663 |