No registrations found.
ID
NL-OMON22747
Source
NTR
Brief title
N/A
Intervention
Outcome measures
Primary outcome
Achievement of euthyroidism (TSH >0.4 mE/L at 3 and 6 months.
Secondary outcome
Development side-effects.
Background summary
N/A
Study objective
N/A
Intervention
Treatment with methimazole and prednisone,
methimazole and sodiumperchlorate
or methimazole, sodiumperchlorate and prednisone.
Public
Academic Medical Center (AMC), Department of Endocrinology and Metabolism,
P.O. Box 22660
W.M. Wiersinga
Meibergdreef 9
Amsterdam 1105 AZ
The Netherlands
+31 (0)20 5669111
w.m.wiersinga@amc.uva.nl
P.O. Box 22660
W.M. Wiersinga
Meibergdreef 9
Amsterdam 1105 AZ
The Netherlands
+31 (0)20 5669111
w.m.wiersinga@amc.uva.nl
Scientific
Academic Medical Center (AMC), Department of Endocrinology and Metabolism,
P.O. Box 22660
W.M. Wiersinga
Meibergdreef 9
Amsterdam 1105 AZ
The Netherlands
+31 (0)20 5669111
w.m.wiersinga@amc.uva.nl
P.O. Box 22660
W.M. Wiersinga
Meibergdreef 9
Amsterdam 1105 AZ
The Netherlands
+31 (0)20 5669111
w.m.wiersinga@amc.uva.nl
Inclusion criteria
TSH <0.4 mE/L, FT4 >25 pmol/l, normal or raised T3 , thyroid peroxidase antibodies <50 kU/l, TBII < 2.0 kU/l, amiodarone use, poor or no visualisation of thyroid gland on 99mTc-pertechnetate scintigraphy, no nodular goiter on ultrasound.
Exclusion criteria
Very critical illness, drug or alcohol abuse, pregnancy, no informed consent.
Design
Study type
:
Interventional
Intervention model
:
Parallel
Masking
:
Single blinded (masking used)
Control
:
Placebo
Recruitment
NL
Recruitment status
:
Recruiting
Start date (anticipated)
:
Enrollment
:
45
Type
:
Anticipated
Positive opinion
Date
:
Application type
:
First submission
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL47 |
| NTR-old | NTR78 |
| Other | : MEC number: 03/271 |
| ISRCTN | ISRCTN06558177 |
Summary results
N/A