No registrations found.
ID
Source
Brief title
Health condition
Bloating, dyspepsia
Opgeblazen gevoel, dyspepsia, maagklachten
Sponsors and support
Intervention
Outcome measures
Primary outcome
1) Gastric measures (MRI): Gastric volume, air and liquid gastric compartments.
2) Subjective ratings of fullness and bloating.
3) Changes in regional brain activity
Secondary outcome
Subjective feelings of appetite, thirst and nausea; obtained on scan days just before and after participants are scanned.
Study objective
Beer induces more bloating than carbonated soft drinks and this effect is more prominent in women compared to men as measured from theh stomach and in regional brain activation.
Study design
Two study days.
Intervention
Consumption of 500 mL beer or carbonated soft drink.
Jac Niessen
Corporate Communicatie
Postbus 9101, 6700 HB Wageningen
Wageningen 6702 PB
The Netherlands
Tel. 0317 485003
jac.niessen@wur.nl
Jac Niessen
Corporate Communicatie
Postbus 9101, 6700 HB Wageningen
Wageningen 6702 PB
The Netherlands
Tel. 0317 485003
jac.niessen@wur.nl
Inclusion criteria
-Age: 18-40 years
-BMI: 18.5 – 25.0 kg/m2
-Healthy (as judged by the participant)
-On average consuming more than 1 unit of beer per month but less than 13 units per week.
-On average consuming more than 1 unit of soft drink per month but less than 13 units per week.
-Willing to be informed about incidental findings of pathology and approving of reporting this to their general physician.
Exclusion criteria
-Drug use or medical conditions which may interfere with normal functioning of the digestive tract.
-Drug use or
medical conditions which may interfere with normal functioning of the circulatory system
-Drug use or medical conditions which may lead to unreliable fMRI results (including, but not limited to
neurological conditions)
-Reported unexplained weight loss or weight gain of > 5 kg in the month prior to pre-study screening
-For women: having the intention to become pregnant, pregnancy during the last 6 months or lactating
- Smoking on average more than one cigarette/cigar a day
-Having a contra-indication to MRI scanning including, but not limited to, metal in the body and claustrofobia
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL5309 |
| NTR-old | NTR5418 |
| Other | NL54050.081.15 : CCMO |