No registrations found.
ID
Source
Brief title
Health condition
Urinary incontinence
Radical prostatectomy
Transperineal ultrasound
Sponsors and support
Intervention
Outcome measures
Primary outcome
To investigate if the displacement of the anorectal junction, ventral and dorsal urethrovesical junction, dorsal point of the bulbus and dorsal point of the striated urethral sphincter have a good intra- and interrater reliability.
Secondary outcome
To compare the displacement of the different structures of urinary continent and incontinent men after radical prostatectomy.
Background summary
Prostate cancer is the most common cancer in men on this moment. Radical prostatectomy is since many years the gold standard for eradication of localized prostate cancer. Urinary incontinence however remains one of the most embarrassing complications after prostatectomy. This project aims to investigate the underlying causes of urinary incontinence by visualising the displacement of several points along the urethra, while contracting the pelvic floor, with transperineal ultrasound.
Study objective
1. To investigate the intra- and interreliability of transperineal ultrasound measurements of the displacement of multiple points along the urethra in men after radical prostatectomy;
2. To compare the relative displacement of urethrovesical junction, anorectal junction and distal urethra during voluntary pelvic floor muscle contractions from preoperative to 3 months postoperative after radical prostatectomy;
3. To compare the relative displacement of urethrovesical junction, anorectal junction and distal urethra during voluntary pelvic floor muscle contractions between continent and incontinent men after radical prostatectomy.
Study design
Group 1 (continent men): Preoperatively and 3 months postoperatively;
Group 2 (incontinent men): Minimum 1 year postoperatively.
Intervention
Both groups will have transperineal ultrasound.
Group 1: Patients who are planned for a radical prostatectomy will have a transperineal ultrasound of the displacement of multiple points along the urethra pre- and postoperatively.
Group 2: Patients who had a radical prostatectomy minimum one year before and are still incontinent will have a transperineal ultrasound of the displacement of the same multiple points along the urethra.
Inge Geraerts
Katholieke Universiteit Leuven
Faculteit Bewegings- en Revalidatiewetenschappen
Tervuursevest 101
Leuven 3001
Belgium
+32 16329120
inge.geraerts@faber.kuleuven.be
Inge Geraerts
Katholieke Universiteit Leuven
Faculteit Bewegings- en Revalidatiewetenschappen
Tervuursevest 101
Leuven 3001
Belgium
+32 16329120
inge.geraerts@faber.kuleuven.be
Inclusion criteria
Continent patients:
1. Patients who will have a radical prostatectomy for localised or locally advanced prostate cancer in the University Hospital Gasthuisberg in Leuven;
2. Patients who can participate in one pre- and one postoperative transperineal ultrasound measurement in the University Hospital Gasthuisberg.
Incontinent patients:
1. Patients who had a radical prostatectomy in the University Hospital Gasthuiberg, minimally 1 year before and are still urinary incontinent;
2. Patients willing to participate in one transperineal ultrasound measurement.
Exclusion criteria
Patients who don't want to participate to the study.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL3516 |
| NTR-old | NTR3678 |
| Other | IWT : 080678 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |