No registrations found.
ID
Source
Health condition
Women in the last trimester of their pregnancy.
Sponsors and support
Intervention
Outcome measures
Primary outcome
Primary outcome is a reference range for a plasma thrombin generation assay and a newly developed whole blood thrombin generation assay.
Secondary outcome
Correlation with peri-partal bleeding.
Background summary
Blood of 120 pregnant women will be analysed for plasma thrombin generation and whole blood thrombin generation to create a reference range for this population.
Study objective
Aim of the study is to receive reference ranges for a plasma and a whole blood thrombingeneration assay.
Study design
In the final trimester before delivery patients comimng to the policlinics and/or for hospital admission will be asked to participate. After informed consent 18ml citrated blood will be drawn during a regular blood drawing.
Intervention
No intervention planned.
This study is observational.
MUMC+
P.Debeyelaan 25
M.D. Lancé
Maastricht 6202 AZ
The Netherlands
marcus.lance@mumc.nl
MUMC+
P.Debeyelaan 25
M.D. Lancé
Maastricht 6202 AZ
The Netherlands
marcus.lance@mumc.nl
Inclusion criteria
All healthy, adult women who are in the final trimester of their pregnancy.
Exclusion criteria
Acquired and inherited coagulation abnormalities.
HELLP-syndrome and pre-eclampsia.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4630 |
| NTR-old | NTR4782 |
| Other | : METC 14-4-063 |
Summary results
BJA-2014: Peri-partum reference ranges for ROTEM thromboelastometry