No registrations found.
ID
Source
Brief title
Health condition
Parkinson
Sponsors and support
Intervention
Outcome measures
Primary outcome
UPDRS-II and III
Secondary outcome
motor aspects (walking, balance), non-motor aspects (mood, cognition), blood biomakers (BDNF, NfL)
Background summary
We will investigate the effects of High Intensity Interval Training on motor and non-motor outcomes in people with Parkinson's disease
Study objective
HIIT improves motor and non-motor outcomes.
Study design
ABACA or ACABA design with B and C being intervention phases and A baseline phases with weekly assessments, total duration28 weeks
Intervention
HIIT and Continuous Aerobic training
Inclusion criteria
1) diagnosis of PD according to brain bank criteria, 2) Hoehn-Yahr stage 1 -3, 3) sufficient cognition to comprehend training instruction (Moca score >21) and 4) able to provide written informed consent.
Exclusion criteria
1) history of neurologic deficits other than PD, 2) severe fluctuating responses to medication, 3) psychiatric, musculoskeletal, cardiac or metabolic disorders prohibiting participation in intensive exercise training.
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8367 |
| CCMO | NLx029.20 |