No registrations found.
ID
Source
Brief title
Health condition
Astma, bronchial hyper responsiveness and bronchial obstruction
Sponsors and support
Intervention
Outcome measures
Primary outcome
EMG parameters correlated to standard lung function test determining its use providing information on the efficiency of treatment
Secondary outcome
The difference in EMG and its recovery between children with less and increased respiratory distress
Background summary
Quantitative lung function methods, such as spirometry and Forced Oscillatory Technique (FOT), are valuable tools for the pediatrician to assess respiratory physiology. Over recent years, electromyography (EMG), a less demanding and non-obtrusive method, has been studied in the assessment of bronchial hyperreactivity, showing promising results. A change in EMG signal is suggested to reflect respiratory distress. Therefore, the EATP study hypothesizes that changes in EMG signal can reflect treatment response, and may provide clinicians with valuable information on treatment efficacy.
Study objective
EMG measurements will reflect treatment response in children referred to the pediatrics department for bronchial hyper responsiveness and/or obstruction, providing clinicians with valuable information on treatment efficiency
Study design
- When patients with bronchial obstruction and hyperresponsiveness are referred to the outpatient clinic, they are asked to participate upon arrival. Informed consent is obtained as well. If the medical situation surrounding the subject is in a more tranquil state, the subject and parents will have the opportunity to read the information more thoroughly and ask as much questions as needed.
- Measurements are conducted before and after every nasal irrigation and salbutamol administration given according to standard care and before discharge.
- Measurements are repeated in case of mandatory follow-up in one week time.
Inclusion criteria
children with bronchial obstruction and bronchial hyper responsiveness in need of bronchodilator treatment, ages: 4 -16 years
Exclusion criteria
Admittance to ICU, children of parents with insufficient knowledge of the Dutch language, children with a pacemaker/ICD, children born prematurely (<32 weeks of gestation)
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL7850 |
| Other | MEC protocol number : K19-29 |