No registrations found.
ID
Source
Brief title
Health condition
Subfertility; Infertility
Sponsors and support
Intervention
Outcome measures
Primary outcome
Primary outcome measure will be live birth rate per patient after one year of treatment.
Secondary outcome
Secondary outcome measures will be embryo quality, clinical pregnancy rate, ongoing pregnancy rate, miscarriage rate, time to pregnancy, birth weight and percentage of children with congenital abnormalities.
Background summary
This study investigates whether the use of G5-medium for the in vitro culture of human preimplantation embryos leads to an improved live birth rate per patient as compared to the use of HTF-medium.
Study objective
To investigate whether the use of G5-medium for the in vitro culture of human preimplantation embryos leads to an improved live birth rate per patient as compared to the use of HTF-medium.
Study design
The duration of the study is three years.
Intervention
Ovarian hyperstimulation, oocyte retrieval and oocyte fertilization will be performed using standard procedures. In the experimental arm, all oocytes and resulting embryos will be cultured in G5-medium and in the control arm, oocytes and resulting embryos will be cultured in HTF-medium.
P.O. Box 22660
Sebastiaan Mastenbroek
Meibergdreef 9
Amsterdam 1100 DD
The Netherlands
+31 (0)20 5663090
S.Mastenbroek@amc.uva.nl
P.O. Box 22660
Sebastiaan Mastenbroek
Meibergdreef 9
Amsterdam 1100 DD
The Netherlands
+31 (0)20 5663090
S.Mastenbroek@amc.uva.nl
Inclusion criteria
Subfertile couples undergoing IVF (in vitro fertilization) or ICSI (intracytoplasmatic sperm injection).
Exclusion criteria
1. Couples undergoing a PGD cycle;
2. Couples for which IVF is used to prevent the transmission of HIV;
3. Couples undergoing a modified natural cycle.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1866 |
| NTR-old | NTR1979 |
| Other | : N/A |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |