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ID
Source
Brief title
Health condition
Stepping responses in healthy subjects and stroke survivors.
Dutch keywords:
Balans
Staan
Lopen
Reactieve voetplaatsing
CVA
Sponsors and support
Intervention
Outcome measures
Primary outcome
Foot placement location and swing time
Secondary outcome
- Distance between center of mass and center of pressure
- Ground reaction forces
- Joint angles
- Joint torques
- Body angular and linear momenta
- Muscle (reflexive) activity levels
Background summary
In daily life the upright human body is continuously challenged by external disturbances, such as gravitational forces and forces originating from interactions with the environment. These disturbances can lead to a loss of balance, which must be acted upon accordingly to prevent a fall. Following a disturbance, proper foot placement is crucial for maintaining balance during both standing and walking. However it is unclear why humans place their foot at a certain location at a certain time following an unexpected balance disturbance. A model based prediction of a suitable foot placement location to maintain balance and prevent falls can have great value in both clinical and robotics fields of research. Investigating foot placement in stroke patients can lead to a better understanding how stroke related complications affect foot placement, and how these might be compensated using supportive devices such as exoskeletons.
Study objective
What is the relation between body states (e.g. center of mass position and velocity) following a change in externally applied pelvic force, and the resulting swing time and stepping location used to maintain balance in standing and walking.
Study design
All instances from perturbation onset up and including to the moment of first, second and possibly third subsequent foot contact.
Intervention
Forces applied at the pelvis during standing and walking to disturb balance and invoke a stepping response.
Inclusion criteria
Healthy subjects :
- between 18 and 30 years of age
Stroke survivors :
- between 18 and 70 years of age
- diagnosed with a hemiparesis as the result of a first ever ischemic stroke
- > 6 months post-stroke (chronic stage)
- functional ambulation category (FAC) 4 : walk independently on level surfaces
- physical condition allows independent walking for at least 3 consecutive minutes
- stable medical condition
- sufficient cognitive abilities (mini-mental state examination >= 22)
- sufficient communication abilities (Utrechtse communicatie onderzoek >= 3)
Both :
- body weight < 100 kg
- has given written informed consent
Exclusion criteria
Healthy subjects :
- has current lower extremity problems or deficiencies (e.g. knee problems, disabilities in walking)
- has (a history of) neurological or balance related disorders
Stroke survivors :
- has (a history of ) other neurological or balance related disorders not related to stroke
Both :
- is using medication that can affect balance control
- is pregnant, or has a chance of being pregnant
- has chronic joint pain
- has orthopedic problems
- has (a history of) cardiac conditions that interfere with physical load
- has (a history of) skin diseases that could result in irritation of the skin underneath the EMG electrodes
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4412 |
| NTR-old | NTR4841 |
| CCMO | NL50450.044.14 |
| OMON | NL-OMON44237 |