No registrations found.
ID
Source
Brief title
Health condition
Biliary atresia
Sponsors and support
Intervention
Outcome measures
Primary outcome
Visualisation of the (remnant) biliary structures.
Secondary outcome
N/A
Background summary
Conventional cholangiography in children with biliary atresia is a cumbersome procedure that is not always successful. Fluorescence cholangiography may provide a simpler, safer method of visualising the (remnant) extrahepatic bile ducts.
Study objective
The diagnosis of biliary atresia may be confirmed by intraoperative fluorescence cholangiography using intravenously or biliary administered indocyanine green.
Study design
Intraoperative imaging.
Intervention
1. Intravenous injection with ICG;
2. Intrabiliary injection with ICG;
3. Imaging using a near-infrared fluorescence camera.
All children receive intravenous injection with ICG. If no signal is received peroperative, intrabillary injection is administered.
JBF Hulscher
Groningen 9700 RB
The Netherlands
+31 (0)50 3611735
JBF Hulscher
Groningen 9700 RB
The Netherlands
+31 (0)50 3611735
Inclusion criteria
Children in whom billiary atresia is suspected scheduled to undergo Kasai portoenterostomy.
Exclusion criteria
1. History of iodine allergy or anaphylactic reactions to insect bites or medication;
2. Presence or history of hyperthyroidism;
3. Severe renal or liver failure.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL2053 |
| NTR-old | NTR2170 |
| Other | UMC Groningen : BA_BICG_UMCG_1 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |