No registrations found.
ID
Source
Brief title
Health condition
Neonates born with the following congenital malformations: gastroschsis, omphalocele and duodenal- or small bowelatresias, who are corrected surgically. Peri- and post-operatively they have a nasogastric tube for gastro-intestinal decompression. If gastric retentions disappear, enteral feeding can be started.
Sponsors and support
Meibergdreef 9
PO Box 22660
1100 DD Amsterdam
Phone +31 20 5669111
Intervention
Outcome measures
Primary outcome
Number of days from the operation to enteral feeding of 120 ml/kg/day.
Secondary outcome
1. Weight gain on day 20 postoperative compared to birthweight;
2. Number of coag. neg. staph. (CNS) sepsis episodes.
Background summary
In neonates born with gastroschisis, omphalocele or intestinal atresias who underwent surgical correction, postoperative MEF is compared to no MEF: number of postoperative days to complete enteral feeding and CNS sepsis episodes are probably less and the weightgain more in the group receiving MEF.
Study objective
With postoperative minimal enteral feeding (MEF) the neonates can be fed completely enteral earlier than without MEF.
Study design
N/A
Intervention
1. 6 x 2 ml feeding (formula or breast) through the nasogastric tube, followed by 30 min. tube closure;
2. Compared to 6 x 30 min. tube closure without feeding;
3. Start enteral feeding if daily gastric retention is less than 25 ml/day.
P.O. Box 7075
R. Baren, van
VU Medical Center,
De Boelelaan 1117
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4442424
r.vanbaren@amc.uva.nl
P.O. Box 7075
R. Baren, van
VU Medical Center,
De Boelelaan 1117
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4442424
r.vanbaren@amc.uva.nl
Inclusion criteria
All neonates with gastroschsis, omphalocele, duodenal- and small bowel atresia who underwent surgical correction.
Informed consent of the parents.
Exclusion criteria
1. No informed consent of the parents;
2. Pre-operative bowel perforation;
3. Per-operative need for a stoma.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL229 |
| NTR-old | NTR266 |
| Other | : N/A |
| ISRCTN | ISRCTN96703143 |