No registrations found.
ID
Source
Brief title
Health condition
Anxiety disorders
Sponsors and support
Erasmus Medical Center-Sophia
Volksgezondheid (national fund public mental health)
-Revolving Fund LUMC
-Sophia Foundation for Scientific Research
Intervention
Outcome measures
Primary outcome
1. Diagnostic status;
2. Anxiety symptoms.
Secondary outcome
1. Depressive symptoms;
2. Other symptoms of psychopathology;
3. Global level of functioning.
Background summary
Anxiety disorders in children and adolescents are common. Cognitive behavioral treatment is effective for most children with anxiety disorders, but some children do not benefit enough and remain anxious. The present study examined the efficacy of individual versus group cognitive behavioral therapy. The present study also examines which factors predict treatment outcome. Participants are children and adolescents from 8 to 16 years old diagnosed with anxiety disorder(s), assessed by the Anxiety Disorders Interview Schedule (ADIS). Children and parents completed self-report measures assessing overall functioning, presence of psychiatric symptoms, anxiety symptoms, depression symptoms, social skills, negative affectivity, anxiety sensitivity and parental rearing practices. Physiological measures are conducted measuring heart rate, breathing, skin conduction, blood pressure and Cortisol concentration in saliva. Genetic factors are also examined, as is attention bias using a probe detection task.
Study objective
1. Group cognitive behavioral treatment is as effective as individual cognitive behavioral treatment;
2. Treatment outcome is predicted by severity of the psychopathology, cognitive variables, social variables, biological variables and environmental variables;
3. Children diagnosed with an anxiety disorder after the first phase of treatment will respond to prolongation of the treatment with active participation of parents.
Study design
N/A
Intervention
Individual cognitive behavioral treatment
or
Group cognitive behavioral treatment.
Endegeesterstraatweg 27
Adelinde J.M. Leeden, van der
Endegeesterstraatweg 27
Oegstgeest 2342 AK
The Netherlands
+31 (0)71 5159600
A.J.M.van.der.Leeden@umail.leidenuniv.nl
Endegeesterstraatweg 27
Adelinde J.M. Leeden, van der
Endegeesterstraatweg 27
Oegstgeest 2342 AK
The Netherlands
+31 (0)71 5159600
A.J.M.van.der.Leeden@umail.leidenuniv.nl
Inclusion criteria
Children and adolescents between 8 and 16 years old, primary diagnosed with at least one of following DSM IV anxiety disorders: separation anxiety disorder, social phobia, generalized anxiety disorder or specific phobia.
Exclusion criteria
1. IQ less than 85;
2. Children who are not proficient in the Dutch language;
3. Somatic disease;
4. Drug related disorder;
5. Pervasive developmental disorder;
6. Selective mutism;
7. Psycho-somatic disease;
8. Schizofrenia or other psychotic disorder;
9. Obsessive compulsive disorder;
10. Post-traumatic stress disorder;
11. Acute stress disorder;
12. Use of medication for anxiety;
13. Concurrent psychotherapy.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL309 |
| NTR-old | NTR347 |
| Other | : 5484 (NFGV) |
| ISRCTN | ISRCTN48511871 |