No registrations found.
ID
Source
Brief title
Health condition
Hemoglobinopathies
Sponsors and support
Intervention
Outcome measures
Primary outcome
Carrier frequence of hemoglobinopathies.
Secondary outcome
1. Serum ferritin;
2. Compliance to prenatal testing;
3. Cost-Effectiveness.
Background summary
In a period of 2 years an unselected group of pregnant females (n = 1000) and a group of newborns (n = 1000) will be screened for hemoglobinopathies.
Primary endpoint is the carrier frequence of hemoglobinopathies, secondary endpoints are the compliance to prenatal testing, iron stores and cost-effectiveness.
Study objective
The carrier frequence of hemoglobinopathies is > 0,05 and screening for primary prevention is cost-effective.
Study design
N/A
Intervention
Unselected group of pregnant females (n = 1000) and a group of newborns (n = 1000) will be screened for hemoglobinopathies.
Leyweg 275
J.L.H. Kerkhoffs
Den Haag 2545 CH
The Netherlands
+31 (0)70 3592004
J.Kerkhoffs@hagaziekenhuis.nl
Leyweg 275
J.L.H. Kerkhoffs
Den Haag 2545 CH
The Netherlands
+31 (0)70 3592004
J.Kerkhoffs@hagaziekenhuis.nl
Inclusion criteria
1. Pregnant females before the 16th week of pregancy and newborns.
2. Informed consent.
Exclusion criteria
Known hemoglobinopathy.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL566 |
| NTR-old | NTR622 |
| Other | MEC : 05-83 |
| ISRCTN | ISRCTN88941850 |
Summary results
<br><br>
Disorders of hemoglobin. Genetics, pathophysiology and clinical managment. Edit by Steinberg et al. Cambridge Univ. Press 2001