No registrations found.
ID
Source
Health condition
Acute exacerbation COPD (AECOPD)
Pneumonia
Acute exacerbatie (longaanval) COPD
Longonsteking
Sponsors and support
* Thermo Fisher Scientific (material support)
Intervention
Outcome measures
Primary outcome
Frequency of radiological pneumonia in exacerbating COPD patients as analysed by low dose-CT
Secondary outcome
* Clinical and/or biochemical predictors (PCT) for radiological pneumonia in COPD patients proven by low dose-CT
* Pulmonary pathology evidenced by low dose-CT
* Phenotype COPD exacerbations based on outcomes of low dose-CT
Study design
Baseline (admission to the hospital)
Day 3 (blood sample)
Follow-up (check medical records at t=30 and t=90)
Intervention
CT-scan (once) and 3 times blood sample
Dionne Braeken
Maastricht
The Netherlands
043-3874448
dionne.braeken@mumc.nl
Dionne Braeken
Maastricht
The Netherlands
043-3874448
dionne.braeken@mumc.nl
Inclusion criteria
* Adults, either sex, older than 40 years of age
* Smoking history of 10 Pack Years or more
* Diagnosis of COPD stages I-IV, class A-D, as defined by the Global initiative for chronic Obstructive Lung Disease (GOLD)
* Doctor's diagnosis of AECOPD (clinical presentation of a patient complaining of an acute change of symptoms that is beyond normal day-to-day variation - baseline dyspnoea, cough and/or sputum production)
* Patients must sign and date an informed consent prior to inclusion in the study
Exclusion criteria
* Progressively fatal disease, or life expectancy <= 6 months
* Women who are breast-feeding or are pregnant
* Patients with mental conditions rendering them unable to understand the nature, scope, and possible consequences of the study
* Patients participating in an intervention study which influences outcomes
* Un-ability to lie flat for the performance of CT-scan
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4817 |
| NTR-old | NTR5318 |
| CCMO | NL49554.068.14 |
| OMON | NL-OMON44303 |