No registrations found.
ID
Source
Brief title
Health condition
implementation, blood management, total hip arthroplasty, total knee arthroplasty, behavior change
implementatie, bloed management, totale heup arthroplastiek, totale knie arthroplastiek, gedragsverandering
Sponsors and support
P.O. Box 9600, 2300 RC Leiden, the Netherlands
- Jon J van Rood, Netherlands Center for Clinical Transfusion Research (Sanquin)
Intervention
Outcome measures
Primary outcome
The primary outcome is the % of patients undergoing primary elective total hip or knee arthroplasty in which EPO or blood salvage is applied.
Secondary outcome
Secondary study parameters are the patient outcomes of the surgery including post-operative hemoglobin (Hb) level, length of hospital stay and number of allogeneic transfusions. Also possible complications will be registered: reactions on EPO use, transfusion reactions due to the use of blood salvage, transfusion reactions due to allogeneic transfusions, other (serious) adverse events.
Background summary
Hospital-clustered RCT comparing a tailored de-implementation intervention with no intervention in 20 hospitals to change the blood management behavior of orthopedic surgeons and anesthesiologists.
Study objective
This study aims to change the blood management behavior of orthopedic surgeons and anesthesiologists in primary elective total hip and knee arthroplasties, using a tailored intervention strategy for de-implementation of EPO and blood salvage.
The hypothesis is that the intervention results in an absolute decrease of 20% in patients receiving EPO or blood salvage in comparison to usual care (control intervention).
Study design
Because the alternative study design, the measurement points are not patient-related but predetermined.
The measurement points are: 1st August to 31 December 2013 baseline. October 1st 2014 to February 28th 2015 follow-up.
The months in between: January 1, 2014 to September 30, 2014 form the intervention period.
Intervention
- Interactive education aimed at orthopedic surgeons and anesthesiologists
- Feedback in an educational outreach visit aimed at orthopedic surgeons and anesthesiologists
- Dissemination and reports on hospital performance/ best practices aimed at orthopedic surgeons and anesthesiologists
- Information letter/ email aimed at other involved professionals (transfusion committee, OR-personnel, pharmacists).
P.O. Box 9600,
V.M.A. Voorn
Leiden 2300 RC
The Netherlands
+31 (0)71-5265139
v.m.a.voorn@lumc.nl
P.O. Box 9600,
V.M.A. Voorn
Leiden 2300 RC
The Netherlands
+31 (0)71-5265139
v.m.a.voorn@lumc.nl
Inclusion criteria
- Hospitals using EPO and/or blood salvage in patients undergoing primary elective THA or TKA on a regular basis (more frequently than in exceptional cases)
- Hospitals performing at least 50 THA and/or TKA on average per 5 months.
Exclusion criteria
- Hospitals considering to abandon the use of EPO or blood salvage on their own initiative
- Hospitals participating in trials that interfere with the use or the discontinuation of EPO or blood salvage
- Hospitals employing the same group of orthopaedic surgeons or anaesthesiologists as a previous included hospital.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL3883 |
| NTR-old | NTR4044 |
| Other | : |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |