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ID
Source
Brief title
Health condition
tobacco use disorder
Sponsors and support
Intervention
Outcome measures
Primary outcome
the change in cue-induced craving (Tobacco Craving Questionnaire – Short Form” (TCQ-SF) as a result of the intervention
Secondary outcome
Firstly, physiological measures for cue-reactivity (skin conductance, heart rate, blood pressure) are measured during 2 exposure sessions (one before and one after intervention).
Secondly, smoking behavior on the follow-up (2 weeks and 3 months after intervention) is tested by means of questionnaires.
Background summary
The aim of the study is to evaluate a retrieval-distractor protocol on cue-induced craving in smokers. The primary objective is to evaluate whether retrieval of smoking memories directly followed by distractor stimuli would lead to a reduced cue-induced craving, i.e. successful disruption of the reconsolidation of the addiction memory. To test this, we will compare two groups of smokers subjected to a motion-assisted modified EMDR procedure in a virtual environment. One group will be exposed to distractor stimuli upon smoking memory retrieval, the other group to a non-distracting control stimulus
Study objective
We expect to see a greater decline in cue-induced craving after intervention in the active group than the control group.
Study design
Patients come to the Amsterdam UMC (location Vumc) for 5 days straight: the middle three days are the intervention days, on the first and last day questionnaires and cue-exposure are carried out
Intervention
Three sessions of 45 minutes, in which the active group, who walk in a virtual environment, are exposed to visual smoke-related stimuli and distractor stimuli. The control group is exposed to neutral stimuli instead of the distractor stimuli.
Inclusion criteria
Men and women aged between 30 and 50 years, who have smoked for at least 10 years and smoke a minimum of 10 (filter) cigrattes per day
Exclusion criteria
Participants with: 1) Neurological disorders 2) lifetime diagnosis or treatment of psychosis or mania 3) other psychiatric diagnoses or treatments in the past year 4) current use of psychopharmaca 5) current substance abuse besides nicotine 6) mobile restrictions 7) unability to understand study procedures
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8581 |
| CCMO | NL63887.029.18 |
| OMON | NL-OMON55689 |