No registrations found.
ID
Source
Brief title
Health condition
obesity
overweight
Sponsors and support
Dutch Heart Foundation
KNAW: Royal Netherlands Academy of Arts and Sciences
Intervention
Outcome measures
Primary outcome
BMI z-score.
Secondary outcome
1. Waist circumference;
2. Bioelectrical impedance (% fat mass);
3. Sum of four skinfolds (mm);
4. Dental health;
5. Sensory evaluation.
Background summary
Obesity results from an imbalance between energy intake and energy expenditure. There is much speculation about foods that are particularly fattening, and sugary drinks are seen as major culprits. It is hypothesized that a high intake of calories from sugary drinks would not be compensated for by reduced food intake at subsequent meals. As a result body weight would increase. In this double-blind, long term, randomized controlled trial the effect of replacing sugar-containing beverages by low-sugar alternatives on body weight and fat mass in children will be investigated.
Study objective
The hypothesis is that intake of liquid carbohydrates is not compensated sufficiently by reducing caloric consumption from other foods. This leads to incomplete compensation for the energy ingested and eventually results in weight gain.
Study design
0, 6, 12 and 18 months.
Intervention
1. Intervention 1: 250 mL per day of sugar-containing lemonade;
2. Intervention 2: 250 mL per day of lemonade low in sugar. The low-sugar drinks are sweetened with artificial sweeteners.
The intervention will take 18 months.
Margreet R. Olthof
De Boelelaan 1085
Amsterdam 1081 HV
The Netherlands
+31 205982522
margreet.olthof@falw.vu.nl
Margreet R. Olthof
De Boelelaan 1085
Amsterdam 1081 HV
The Netherlands
+31 205982522
margreet.olthof@falw.vu.nl
Inclusion criteria
1. Healthy school going boys and girls;
2. Age 5 years and older, children still have to be in elementary school at the end of the study;
3. Children who already habitually consume 250 mL per day or more of sugary drinks.
Exclusion criteria
1. Using medication or under medical treatment for obesity;
2. Any acute or chronic disease such as diabetes, growth disorders, celiac disease, or serious gastroenterological diseases;
3. Medical history or surgical events known to interfere with the study;
4. Participation in another intervention trial up to 3 months before and during the study, if the intervention interferes with the current study;
5. Physical disabilities that hamper the measurements;
6. Intention to change location of residence and primary school during the study period.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1695 |
| NTR-old | NTR1796 |
| Other | ZONMW / NHS : 120520010 / 2008B096 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd |