No registrations found.
ID
Source
Brief title
Health condition
neuroblastoma
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary study endpoints are the number of lesions and sites of disease detected with 18F-mFBG PET-CT
compared to the current imaging standard of care, 123I-mIBG scan using the SIOPEN imaging scoring method for
skeletal lesions and the total number of detected soft tissue lesions
Secondary outcome
o Determine optimum imaging time of 18F-mFBG PET CT(60 min vs 120-150 min post injection)
o Determine the estimation of radiation absorbed dose of 18F-mFBG
o Adverse events of 18F-mFBG injection and PET CT s
Background summary
To compare [18F]mFBG PET-CT imaging for neuroblastoma patients with the current standard of imaging, [123I]mIBG SPECT, using the SIOPEN score for skeletal lesions and the number of detected soft tissue lesions as endpoints.
Study objective
[18F]mFBG PET-CT is probably better able to define neuroblastoma compared to the current imaging standard [123I] mIBG.
Study design
After 10 patients (6 months) and 20 patients (1 year)
Intervention
[18F]mFBG PET CT
Inclusion criteria
patients with a (clinical suspicion of) neuroblastoma who are referred for [123I] mIBG imaging, 0-18 years of age
Exclusion criteria
pregnancy of the patient and above 18 years old
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8152 |
| CCMO | NL70903.041.19 |
| OMON | NL-OMON49035 |