The effect of cannabidiol (40mg) on fear conditioning

- Male or female volunteers between 18 and 40 years.

- Judged to be in good physical and mental health on the basis of the
medical history according to self-report.

- Have a normal binocular acuity, corrected or uncorrected.

- Female participants must declare they are on reliable birth control.

A potential subject who meets any of the following criteria will be excluded from participation in this study:

- Have a history of any disease, e.g. neurological disorders, psychiatric disorders, which in the opinion of the investigator may confound the results of the study.

- Present any other conditions in that in the investigators’, the subjects’ personal or the physicians’ opinion may confound the results of the study.

- History of psychotic disorder/psychosis and/or having a first/second degree family member with (a history of) psychotic disorder/psychosis.

- Current diagnosis of an Axis I or Axis II psychiatric disorder, or suffering from an Axis I or Axis II psychiatric disorder within 4 weeks prior to the study.

- Current respiratory disease or history of respiratory disease.

- Current asthma or history of asthma.

- Acute cardiac disease and/or history of cardiac disease.

-  History of abuse or current regular use of cannabis more than once a week.

-  Have been using psychoactive drugs in the four weeks prior to the study.

- Known hypersensitivity to CBD.

- Exposed to cannabinoids with adverse reactions.

- Have a history of severe allergy or general drug hypersensitivity.

-  Current drug use or indications, from urine screening, of current drug use.

- History of epilepsy.

- Reduced startle activity, defined as no discernible response in at least 3 startle stimuli presented at screening.

- Pregnancy, i.e., a positive β-HCG urine test.

- Lactating.