No registrations found.
ID
Source
Brief title
Health condition
BPH or fertility problems
Sponsors and support
Intervention
Outcome measures
Primary outcome
We expect a correlation between serum level testosterone and basic cognitive functions such as cognitive speed and cognitive control.
Secondary outcome
The relative contributions of age and testosterone level to cognitive functions will be established.
Background summary
Recent research showed a correlation between age related changes in hormone levels and cognitive decline and the emergence of Alzheimer disease in both men and women.
Most research however is conducted in women.
The aim of this study is to further investigate the relation between testosterone level and cognitive functioning in older men. In order to determine testosterone level, total-, SHBG- and albumin bound and bioavailable testosterone will be measured.
Three cognitive computer tests are aimed to measure basal information processing speed, ability to suppress irrelevant stimuli and visuospatial perception, respectively.
Two out-patient groups will be included:
1. BPH-patients in the age of 55-75, and
2. patients with fertility symptoms in the age of 20-45 years.
Study objective
Serum testosterone levels in men will be related to basic cognitive functions, such as mental processing speed and cognitive control.
Study design
N/A
Intervention
Computer tests.
P.O. Box 1738
J.W. Strien, van
Rotterdam 3000 DR
The Netherlands
+31 (0)10 4088787
vanstrien@fsw.eur.nl
P.O. Box 1738
J.W. Strien, van
Rotterdam 3000 DR
The Netherlands
+31 (0)10 4088787
vanstrien@fsw.eur.nl
Inclusion criteria
1. Age between 55 and 75 or age between 20 and 45;
2. Urological complaints suspected to be BPH or fertility symptoms;
3. Subjective healthy impression.
Exclusion criteria
N/A
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL365 |
| NTR-old | NTR404 |
| Other | : A300413 |
| ISRCTN | ISRCTN42645787 |