No registrations found.
ID
Source
Brief title
Health condition
Dilated cardiomyopathy, idiopathic, familial, genetic, sporadic
Sponsors and support
Intervention
Outcome measures
Primary outcome
- Mortality
Secondary outcome
- (co)morbidity
- tissue specific outcomes
Background summary
UNRAVEL is the first multidisciplinary Dutch study where patients’ material and medical information is combined and provides access for all medical centers. The cohort exists of 1600 patients who have been diagnosed with a cardiomyopathy, or received heart transplantation at indication. This cohort will combine genetic data with biopsies performed and transplantation data registered by physicians starting from the 1980’s. Biobank material included are tissue, blood and DNA.
Study objective
We hypothesise that in 50% of iDCM patients a genetic cause/predisposition can be found
Study design
1. At presentation
2. After diagnosis
3. Follow-up till transplantation or death
Intervention
None
F.W. Asselbergs
Department of Cardiology, Division Heart & Lungs
University Medical Center Utrecht
Room E03.511
Utrecht 3508 GA
The Netherlands
f.w.asselbergs@umcutrecht.nl
F.W. Asselbergs
Department of Cardiology, Division Heart & Lungs
University Medical Center Utrecht
Room E03.511
Utrecht 3508 GA
The Netherlands
f.w.asselbergs@umcutrecht.nl
Inclusion criteria
- Dilated cardiomyopathy
- Hart transplantation from 1980 - 2014 in the UMC-Utrecht
- Assist-device from 1985 - 2014 in the UMC-Utrecht
- Genetical testing performed from the UMC-Utrecht for hereditary cardiomyopathies
Exclusion criteria
- Inconsistent or missing electronic patient files
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4714 |
| NTR-old | NTR4859 |
| Other | : METC 12/387 |