No registrations found.
ID
Source
Brief title
Health condition
Hemispatial neglect
Sponsors and support
Revalidatiecentrum De Hoogstraat
Rembrandtkade 10 3583 TM Utrecht
Fax 030 251 1344
Intervention
Outcome measures
Primary outcome
1. Star cancellation;
2. Letter cancellation;
3. Line bisection;
4. Landmark test;
5. Copying;
6. Symmetrical photos;
7. Mental representations.
Secondary outcome
1. Balance board;
2. Mobility Assessment Course;
3. Postural Assessment Scale for Stroke Patients;
4. Subjective Neglect Questionnaire;
5. Catherine Bergego Scale.
Background summary
Unilateral spatial neglect occurs frequently following a brain lesion in especially the right hemisphere (25-30% of all stroke patients, Appleros et al, 2002), resulting in a failure to report or respond to stimulation in contralesional hemispace. Prism adaptation is the most widely studied method to alleviate the symptoms of neglect. Effects of a single session of prism adaptation have been reported across clinical measures, but also in more daily situations, such as wheelchair navigation (Rossetti et al, 1999) and postural control (Tilikete et al, 2001). The current study will focus on the effects of an intensive programme of exposure to prism adaptation (i.e. daily exposure during two weeks) and whether more permanent changes in spatial awareness can be objectified. To assess the effects of prism adaptation in the proposed study, patients will receive either prism adaptation or sham adaptation. We expect longer-lasting, more general beneficial effects after prism adaptation compared to sham adaptation.
Study objective
The current study will focus on the effects of an intensive programme of exposure to prism adaptation (i.e. daily exposure during two weeks) and whether more permanent changes in spatial awareness can be objectified. To assess the effects of prism adaptation in the proposed study, patients will receive either prism adaptation or sham adaptation. We expect longer-lasting, more general beneficial effects after prism adaptation compared to sham adaptation.
Study design
1. Baseline (T0);
2. After 1 week of PA (T1);
3. After 2 weeks of PA (T2);
4. 1 week after ending PA (T3);
5. 2 weeks after ending PA (T4);
6. 4 weeks after ending PA (T5);
7. 12 weeks after ending PA (T6).
Intervention
The prism adaptation procedure will be similar to that employed by Rossetti et al (1998), with the exception that it will be repeated on a daily basis for 2 weeks. Prism adaptation will be performed with a pair of goggles fitted with wide-field point-to-point prismatic lenses, inducing a rightward optical shift of 10°.
Sham adaptation will be performed with a pair of goggles fitted with plain lenses (i.e. no optical shift).
Rembrandtkade 10
Tanja C.W. Nijboer
Utrecht 3583 TM
The Netherlands
+31 (0)30 2533572
t.c.w.nijboer@uu.nl
Rembrandtkade 10
Tanja C.W. Nijboer
Utrecht 3583 TM
The Netherlands
+31 (0)30 2533572
t.c.w.nijboer@uu.nl
Inclusion criteria
1. Patients with hemispatial neglect;
2. 18-85 years of age;
3. No history of psychiatric disorders and/or substance abuse.
Exclusion criteria
1. < 18 years of age, >85 years of age;
2. History of psychiatric disorders and/or substance abuse;
3. Unable to perform neuropsychological screening and/or tests.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL2956 |
| NTR-old | NTR3278 |
| Other | : |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |