The aims of the study are fourfold: 1) to assess dual-task walking performance in patients with late sequelae of polio and compare this to dual-task walking performance of age-matched healthy controls; 2) to investigate the reproducibility of a dual…
ID
Source
Brief title
Condition
- Muscle disorders
- Neuromuscular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Walking performance, assessed with a 2-min walking tests and a dual-task
walking test.
The 2-min indoor walking test will be performed on a closed marked indoor
trajectory. The indoor oval track has a length of 50 m. Subjects are instructed
to walk at a self-preferred walking speed for 2 minutes. The walking distance
will be measured.
2) the dual task walking test consists of a 50m walking test combined with a
secondary cognitive task. In this test subjects are instructed to walk, on a
marked trajectory, a distance of 50m twice at their own speed with their normal
walking aid (if needed) without stopping. The first 50m walk will be performed
without a secondary task. During the second 50 m walk, subjects will solve
orally presented arithmetic problems while walking. Trial duration of each
trial will be recorded. The total time of the 2 trials, the difference between
the 2 trials and walking velocity at the first 50m walk will be analyzed.
The incidence of falls will be based on the subject*s self report. A
questionnaire will be administered, addressing demographic data, frequency of
tripping, frequency and description of falls over the last 12 months, their
consequences, and community services utilized.
Secondary outcome
Quadriceps muscle strength will be measured with a Biodex dynamometer.
Background summary
In older subjects, weakness of the lower limbs increases the risk of falls,
particularly in situations in which the whole body weight is placed on 1 leg.
Persons previously affected by poliomyelitis (polio subjects) commonly have
long-standing muscle weakness, often in the lower limbs. These patients are
often unstable when standing and walking, and they report frequent falls
(Cosgrove et al 1987; Silver and Aiello 2002, Lord et al. 2002). In frail
elderly subjects and patients with Parkinson, dual-task walking tests have been
used to identify individuals at-risk for falling. It is not known whether
dual-task walking tests can predict falls in polio subjects.
Study objective
The aims of the study are fourfold: 1) to assess dual-task walking performance
in patients with late sequelae of polio and compare this to dual-task walking
performance of age-matched healthy controls; 2) to investigate the
reproducibility of a dual-task walking test
3) to determine the frequency of falls over the last 12 months, circumstances
surrounding them, and the consequences of falls and 4) to investigate the
association between dual-task walking performance and incidence of falls in
patients with late sequelae of polio.
Study design
Study design: a cross-sectional study.
Study burden and risks
Patients with late effects of poliomyelitis will visit the department of
Rehabilitation AMC twice. During the first visit they will perform the 2
walking tests. Measurement of quadriceps strength will be performed. The
questionnaire on fall events will be administered. During the second visit, the
walking tests will be repeated.
No risks are associated with performing the walking tests at a self-preferred,
comfortable walking speed. Sufficient rest will be provided between the walking
tests.
Healthy control subjects will visit the department of Rehabilitation once.
During this visit they will perform the 2 walking tests and quadriceps strength
will be measured.
Postbus 22660
1100 DD Amsterdam
Nederland
Postbus 22660
1100 DD Amsterdam
Nederland
Listed location countries
Age
Inclusion criteria
Patients: 1) diagnosis of poliomyelitis; 2) ability to walk 50 m with or without walking aid.
Controls: good health
Exclusion criteria
1) impaired vision; 2) hearing loss.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL11978.018.06 |