To obtain a calibration measure for driving in the DASS driving simulator and secondly to obtain a calibration measure for measuring ERPs during driving in the DASS driving simulator. Therefore, simulated driving and attentional processes during…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
alcoholgebruik
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary study parameters of the study are the steering error of the
simulated driving task, de amplitudes of the recorded event-related potentials,
and the reaction times of the auditory oddball-task.
Secondary outcome
N.v.t.
Background summary
In future research the effects of pharmacological manipulations on driving
performance and attentional processes during driving (by measuring ERPs) will
be investigated in the DASS driving simulator. There is no calibration data
available with regard to driving performance in the DASS nor for measuring ERPs
simultaneously. Because the effects of alcohol are well known, measuring
driving performance and ERPs in the DASS under influence of alcohol could
provide a calibration measure. Therefore, we propose to study simulated
steering performance and ERPs measured during an oddball paradigm, presented
during driving and non-driving, under influence of 5 dosages alcohol (0,0 -
0.02 - 0,05 - 0,08 - 0,1 % BAC).
Study objective
To obtain a calibration measure for driving in the DASS driving simulator and
secondly to obtain a calibration measure for measuring ERPs during driving in
the DASS driving simulator. Therefore, simulated driving and attentional
processes during driving, indicated by ERPs recorded during an auditory oddball
task, will be investigated under influence of alcohol. This way a calibration
measure for future research with pharmacological manipulations in the DASS with
measurement of ERPs will be obtained. The effects of pharmacological
manipulations in future research can be compared with the effects of the
different alcohol dosages from this study.
Study design
Participants take part in the study for 2-6 weeks. Each participant will
participate 5 days (3,5 hours per day). Participation will include doing a
simulated driving task, an auditory oddball paradigm and doing the simulated
driving task while an auditory oddball paradigm is presented simultaneously and
ERPs are recorded.
Intervention
Intervention will consist of five dosages of alcohol: (0,0 - 0.02 - 0,05 - 0,08
- 0,1 % BAC).
Study burden and risks
The risk for the volunteer is very small. There is no risk involved in
performing the computertest (simulated driving test) during which ERPs are
measured. The alcohol dosages are relatively low and correspond with the normal
use of social drinkers.
Sorbonnelaan 16
3584 CA Utrecht
Nederland
Sorbonnelaan 16
3584 CA Utrecht
Nederland
Listed location countries
Age
Inclusion criteria
Social drinker (mean < 21 glasses of alcohol per week), no psychological or physical complaints, possesion of a valid drivers license, normal static binocular acuity, normal hearing
Exclusion criteria
Psychological or physical complaints, use of medication, excessive use of alcohol and/or drugs
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL14191.041.06 |