To determine the clinical feasibility and performance of continuous, non-invasive FAP recording by ABM100 as a replacement of intra-arterial pressure in adult patients. Specifically, a) magnitude of pressure gradient distortion of the FAP pulseā¦
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
circulatie monitoring van patienten tijdens narcose
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
- Offset of finger blood pressure measurement in comparison to intra-arterial
pressure
Secondary outcome
- easiness of finger cuff application (5 point scale)
Background summary
Continuous non-invasive measurement of finger arterial pressure (FAP) in humans
was introduced both for research purposes and for clinical medicine. The
Finapres device has been shown to provide a useful alternative for continuous
intra-arterial measurement in a variety of situations specifically for research
purposes. Thus far technical problems related to improper finger cuff wrapping
and low plethysmogram with cold fingers have limited application of
non-invasive pressure monitoring in clinical medicine. To fill this gap a new
monitor ABM100 with better easy-to-use finger cuffs has been developed.
Study objective
To determine the clinical feasibility and performance of continuous,
non-invasive FAP recording by ABM100 as a replacement of intra-arterial
pressure in adult patients. Specifically, a) magnitude of pressure gradient
distortion of the FAP pulse waveform, b) effects of vasoconstriction on pulse
wave disparity, c) effects of reduction of left ventricular ejection period on
IAP vs. FAP amplification; d) absolute level offset of systolic, diastolic and
mean finger arterial pressures, e) loss of measurement time and f) easiness of
finger cuff application and device control are determined.
Study design
Open prospective study in 30 patients admitted to the AMC for elective surgery
who are provided for with an arterial line for monitoring purposes during
general anesthesia.
1) Informed consent
2) A finger cuff is applied to the mid-phalanx of the middle finger of the
dominant arm; the pressure transducer and the finger cuff are positioned at
heart level.
3) Continuous finger arterial and intrabrachial pressures are measured
simultaneously. In the first minute of measurement the positions of the finger
cuff and pressure transducer are checked for possible hydrostatic level errors
and, if necessary, readjusted.
Study burden and risks
none
Meibergdreef 9
1105 AZ Amsterdam
Nederland
Meibergdreef 9
1105 AZ Amsterdam
Nederland
Listed location countries
Age
Inclusion criteria
- general anesthesia
- intra-arterial monitoring
Exclusion criteria
Serious symptomatic peripheral vascular disease.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL14707.018.06 |