1. To investigate whether the currently used hay fever forecast correlates with the symptoms that grass pollen allergic patients report directly using a new communication system that allows direct control, and whether the model can be improved.2.…
ID
Source
Brief title
Condition
- Allergic conditions
- Upper respiratory tract disorders (excl infections)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
To develop and validate a multi-day hay fever forecast
Secondary outcome
1. To (re)validate the current hay fever forecast using modern communication
technology
2. To develop a system in which patients can enter daily symptom scores by
mobile telephone or the internet in order to obtain prompt and therefore more
reliable registration of symptoms.
Background summary
Pollen allergy is an increasing problem, and among the airborne pollen, grass
pollen are considered one of the main causes of pollen allergy in Europe. Hay
fever forecasts that predict the symptoms patients can be expected to
experience the next day are extremely important for the self management of
these patients since it allows them to adjust their activities or medication
use. This project aims to re-validate the current hay fever model and to
develop a new multi-day hay fever forecast model.
Study objective
1. To investigate whether the currently used hay fever forecast correlates with
the symptoms that grass pollen allergic patients report directly using a new
communication system that allows direct control, and whether the model can be
improved.
2. Development of a multi-day hay fever forecast based on the multi-day weather
forecast and the grass pollen counts in previous years and the hay fever
symptoms of patients.
3. Development and application of an ICT system for collection and recording of
daily hay fever symptom scores.
Study design
This study is an observational study in which symptom scores of patients will
be recorded on a daily basis during grass pollen season.
Patients will also be asked to fill in quality of life questionnaires (EQ-5d,
RQLQ)and activity scores.
Study burden and risks
Inclusion procedure:
patients will undergo a skin prick test and blood test to evaluate their
allergic status, which is a procedure attended with minimal discomfort and risk
for the patient. Some patients will have to undergo a nasal provocation score
to evaluate their allergic complaints. Again, this procedure is attended with
minimal risk and mild discomfort since patients are expected to develop only
complaints of the nose and eyes, comparable with their hay fever complaints.
Study:
patients have to send in their symptom score on a daily basis; additionally,
they will be asked once a week to send in additional symptom scores and to fill
in a quality of life questionnaire during and after season. This will cause no
discomfort or risk for the patient.
Postbus 5
3830 AA Leusden
Nederland
Postbus 5
3830 AA Leusden
Nederland
Listed location countries
Age
Inclusion criteria
rhinoconjunctivitis due to grass pollen allergy
age between 14 and 60
living in Zuid Holland
Exclusion criteria
pregnant or breastfeeding
serious illness (e.g.malignancy, autoimmune disease, cardiovascular morbidity)
asthma treated otherwise than B2 mimetics on demand
disorders of the nose interfering with hay fever symptoms (nasal polyps, concha hypertrophia, septumdeviation exceeding 50%)
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL15230.058.06 |