The aim of this study is to validate a protocol for ultrasonographic hepatic fat assessment, by means of Magnetic Resonance Imaging technique (MRI) as gold standard.
ID
Source
Brief title
Condition
- Glucose metabolism disorders (incl diabetes mellitus)
- Hepatic and hepatobiliary disorders
- Lipid metabolism disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Amount of liver fat: pixel intensity (mode, mean, sd) for ultrasonography and
peak areas (H2O : fat) for MRI.
Secondary outcome
Body mass index, waist circumference, blood pressure.
Background summary
Cardiovascular disease is primary dead cause number 1 in the western
population, making studies on early risk factors mandatory. Several studies
suggest that the amount of liver fat may be a predictor for future
cardiovascular disease. Ultrasonography is an attractive technique for
performing large epidemiologic field studies.
Study objective
The aim of this study is to validate a protocol for ultrasonographic hepatic
fat assessment, by means of Magnetic Resonance Imaging technique (MRI) as gold
standard.
Study design
Validation study
Study burden and risks
Burden: Non-invasive ultrasonography, lying motionless for a long time (40 min)
with noise in the MRI scanner.
Risks: Small
Hanzeplein 1
9700 RB Groningen
Nederland
Hanzeplein 1
9700 RB Groningen
Nederland
Listed location countries
Age
Inclusion criteria
Differences with other participants: a study population as heterogenous as possible. However, this does not guarantee large difference in the amount of liver fat.
Exclusion criteria
viral hepatitis, cirrosis
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL15584.042.06 |