The goal of this study is to develop an optimal traning program that had good physiological explanations and on the other hand the limitations experienced by the patients has to be studied. With positive findings, this program can be embedded in the…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
nieuwvormingen, (1)bijwerkingen inherent aan de behandeling: chemotherapie en bestraling. (2)Deconditionering
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Physical capacity (muscle strength and condition), body composition, fatigue,
quality of life and feeding.
Secondary outcome
not of application
Background summary
cancer is an invasive disease. This disease and his treatment have invasive
consequences on the quality of life of the patient. Research shows that 75-96%
of all cancer patients treated with chemotherapy and 75-100% of cancer patients
treated with radiotherapy have complaints of fatigue. This fatigue has
influence on the daily functioning. The causes of fatigue are complex and
multifactorial. Psychological and physical factors that follows after cancer
plays a role. A greater part of medical docters prescribed rest for optimal
recovery. According to recent understandings this appears not the good advice.
Recent studies demonstrate that physical training has a significant effect of
the quality of life and cancer related fatigue. De physiological changes after
traning are poor understood. In the Netherlands experience has gained from the
"integraal kankercentrum Limburg in revalidation clinic Hoensbroek and
Hornerheide" with a revalidaton program for (ex)cancer patients called "Herstel
en Balans". This program was very positive judged by patients and their
trainers.
Study objective
The goal of this study is to develop an optimal traning program that had good
physiological explanations and on the other hand the limitations experienced by
the patients has to be studied. With positive findings, this program can be
embedded in the regular treatment of cancer patients. With this reasearch,
understandings about physiological parameters and changes due to training are
gained, which can result in optimalization of the training program in the
future. Second, understandings about the appearance of limitations on
cardiopulmonary and muscular level are gained, which excist as side effects of
chemotherapy. Third, understanding in body compensation changes in cancer
patients after chemotherapy before and after physical training are gained. Form
literature is known that body compensition after chemotherpay improved
significantly. By trainings intervention and guidelines for healthy foods, this
program tries to changes the body compensition positively.
Study design
Intervention research with as intervention a physial trainings program during
18 weeks under supervision of a specialized physiotherapist. Indication for
intervention: cancer patients treated with chemotherpay and/or radiotherapy.
The program focusses on improving fatigue, cachexia, deconditioning and
obesity. A control group without intervention is applied, because no physical
training excist or was offered at the time of diagnosis.
Intervention
the intervention consist of a physical part during 18 weeks and a psychological
part. First 12 weeks the accent lies on strength training with exercises for
different muslce groups. From week 13 until week 18 patients train once a week
under supervision of a physiotherapist, with accent on more condition, hold
the muscle strength and pleasure in sports.
Study burden and risks
not of application
De run 4600
5500 MB Veldhoven
NL
De run 4600
5500 MB Veldhoven
NL
Listed location countries
Age
Inclusion criteria
Patients with cancer with curative treatment with chemotherapy in Maxima Medical Centrum Veldhoven.
Chemotherapy at least 6 weeks and maximal 52 weeks
Motivated to follow the program
Be able to follow the program under profesional supervision
Logistic possible to follow the program
age 18-65 years, treated with chemotherapy from 2001, no co-morbidity
Exclusion criteria
In general daily life dependent of care
Low physical capacity (sitting, laying and under 100 meter walking)
Cognitive disturbances or emotional very weak
Severe side effects of medication
Other severe diseases responsible for physical activity intolerance
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL18846.015.07 |