Primary goal:Determination of the number of MRSA-carriers among persons in the direct surroundings of a person (index) with an infection by MRSA.Secundary goal:1. To determine if and how MRSA-colonisation spontaneously (dis)appears or spreads among…
ID
Source
Brief title
Condition
- Bacterial infectious disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
MRSA-positvity by age en gender:
1. Percentage op people colonised with an identical MRSA-strain as the index's
from all the direct contacts of this index .
2. In the total studypopulation, in the group without eradication, in the group
with eradication of the index only and in the group with eradication of both
index and contacts:
- Percentage colonised with MRSA that is free of MRSA after respectively 3 and
6 months.
- Percentage patients that is free of MRSA after respectively 3 or 6 months.
Secondary outcome
How is the relation between:
1. Colonisation by MRSA and age, gender, MRSA-type, degree of contact,
skinleasions and comorbidity.
2. Colonisation by MRSA after 3 months and age, gender, MRSA-type, degree of
contact, skinleasions and comorbidity.
3. Colonisation by MRSA after 6 months and age, gender, MRSA-type, degree of
contact, skinleasions and comorbidity.
Background summary
Until in the nineties Metihicilline Resistent Stapyloccus Aureus (MRSA) nearly
only occurrred in hospitals. In recent years MRSA-strains are diagnosed outside
hospitals (Community-Acquired MRSA or CA-MRSA). This happens all around the
world. In the Netherlands MRSA-strains are still rare. A possible explanation
is the 'search- and destroy' policy in hospitals and the restrictive
prescribing of antibiotics. Little is known about the spread of MRSA in the
general public at community level. It is important to get more information
about the prevalence of MRSA at community level in order to get more insight in
the dynamic spread of MRSA and the evaluation of current prevention and
treatment policies.
Study objective
Primary goal:
Determination of the number of MRSA-carriers among persons in the direct
surroundings of a person (index) with an infection by MRSA.
Secundary goal:
1. To determine if and how MRSA-colonisation spontaneously (dis)appears or
spreads among a index-cases with an MRSA-infection and his or hers surroudings.
2. To determine if there is a difference in disappearing or spreading of
MRSA-colonisation if irradication of index-cases and/or their surroundings is
pursued or not.
Study design
Descriptive
Study burden and risks
People can become anxious if they are colonised with MRSA.
Postbus 584
9700 AN Groningen
Nederland
Postbus 584
9700 AN Groningen
Nederland
Listed location countries
Age
Inclusion criteria
All persons with an MRSA-infection, not being a Veterinary MRSA.
Living in an family (ie not in hospital, nursing home or alone)
On voluntary basis.
Exclusion criteria
Not willing to participate.
Living in hospital or alone
Veterinary MRSA (infected from cattle).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL18768.042.07 |