Pimary objective: visualization of a cognitive switch on a single trials basis using electroencephalographySecondary Objective(s): investigation of the CSP technique and its relation with the cognitive tasks. Two main questions will be addressed:1)…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Healthy males and females
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Main study parameter is the differentiation between the two cognitive task
which is operated from the classification with CSP.
Secondary outcome
Secondary parameters are the neurocorrelate of the switch in the beta range
rhythm and the similaraty of the dynamics of the cognitive and motor switch
Background summary
We aim to develop a technique which permit the visualization of cognitive
switches in a single trial basis. de Jong (in preparation) used Common Spatial
Patterns analysis (CSP; Koles, 1991) to successfully (95% accuracy) visualize
the neural correlates of task switching (a burst in the beta rhythm of the EEG)
using a motor task. In this experiment we are trying to replicate de Jong
findings using a cognitive task-switching paradigm. Given that CSP is more
sensitive for tasks with different topographies we are going to use a task with
a mathematical component, which has a stronger left hemispheric component; and
a color matching task, which is know to have a stronger right hemispheric
component.
Recently Brown and Williams (2005) state a relationship between basal ganglia
and beta rhyhtm (8-30 Hz), for which the beta rhythm would be the frequency
between which the basal ganglia communicate the *go* signal to the motor areas
the instant before a voluntary movement. The beta burst reported from de Jong
(in preparation) seems to reflect the neural correlate of this kind of
interaction.
Study objective
Pimary objective: visualization of a cognitive switch on a single trials basis
using electroencephalography
Secondary Objective(s): investigation of the CSP technique and its relation
with the cognitive tasks. Two main questions will be addressed:
1) Is the neurocorrelate of the swicth still in the beta range rhythm (i.e. 20
hz)?
2) Are the dynamics of the cognitive and motor switch similar (i.e. burst
activity)?
Study design
Individuals will participate to one experiment where EEG will be measured while
performing a task switching task. Task switching implies that participants
respond to the same stimulation depending on what task they have to perform.
Usually the task series is represented in the form A, A, B, B, A, A, B, B, A,
*, where A is the first task and B the second. Swithching cost will be
observerd in the change from task A to B and from task B to A. An equation
similar to 3 + 4 = 9 will be displayed and participants will have, in the
math-match task, to judge if the equation is true or false; whereas in the
color-match task participants will have to judge if the color of the font of
the first and last item match. 50 % of the trials will be correct matches.
Participants will know which task will follow to the one that they are
currently performing and they are instructed to prepare to the following task
each as soon as they are ready with the task at hand. CSP will analyse the EEG
measured during this preparation period and it will used them for the
classification and differentiation between the *switch* and the *non-switch*
trials
Study burden and risks
EEG experiments are not invasive. The nature of stimulation is smilar to that
used regulary in body image research and result in a temporary mild discomfort
in healthy humans. All participants will be debriefed about the experiment.
a. deusinglaan 2
9713 AW
Nederland
a. deusinglaan 2
9713 AW
Nederland
Listed location countries
Age
Inclusion criteria
Healthy individuals, who did not suffer from serious head trauma
Between 18 and 40 years
Healthy right-handed males and females
Native Dutch speaker
Exclusion criteria
Males and females younger than 18 and older than 40 years.
Males and females who are left-hand dominant.
Males and females with reading disabilities
Males and females that use drugs or medicines that could impair cognitive abilities
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL21266.042.07 |