Can inertial sensors be used to detect upper airwayobstruction?
ID
Source
Brief title
Condition
- Upper respiratory tract disorders (excl infections)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The measurements of the inertial sensors will be related to the measured tidal
volumes and airway pressures, as obtained at the various levels of airway
obstruction.
Secondary outcome
The measurements of respiratory induction plethysmography as well as clinical
signs of airway obstruction will be recorded, as obtained at the various levels
of airway obstruction.
Background summary
The function of the human upper airway is to garantee unobstructed passage of
air to and from the lungs. This can only be accomplished by a complex
interaction of anatomical factors, muscles and neurological functions.
Perioperatively this interaction is negatively influenced by agents used for
general anesthesia and/or sedation, as well as by agents used for postoperative
analgesia. Therefore, it is not surprising that this can result in airway
obstruction. After several minutes, airway obstruction will lead to hypoxemia,
which ultimately will increase morbidity and mortality. It would be ideal if
airway obstruction could be directly monitored in stead of the effects
resulting from the obstruction.
At present, sensors to detect upper airwayobstruction are far from ideal, so
there is a great need for more reliable airway obstruction sensors. Inertial
sensors might be helpfull in detecting upper airway obstruction.
Study objective
Can inertial sensors be used to detect upper airwayobstruction?
Study design
Preoperatively, inertial sensors als well as routine perioperative monitors
will be applied.
During spontaneous ventilation under general anesthesia, several levels of
airway obstruction will be induced for very short periods of time (30 seconds).
The period of measurements will take 10 minutes in total.
Intervention
During spontaneous ventilation under general anesthesia, several levels of
airway obstruction will be induced for very short periods of time (30 seconds).
Study burden and risks
As the airway obstruction will be induced during general anesthesia, patients
will be unaware of the obstruction. We consider the risks of this study to be
minimal. Obviously, the sensors which are specific for this study, will comply
to all electrical safety requirements applicable to the operation room
environment.
Meibergdreef 9
1105 AZ Amsterdam
Nederland
Meibergdreef 9
1105 AZ Amsterdam
Nederland
Listed location countries
Age
Inclusion criteria
ASA (American Society of Anesthesiology) class 1-3 patients, age > 18 years, without signs of symptoms of upper airway obstruction or respiratory problems, scheduled for a surgical procedure under general anesthesia.
Exclusion criteria
Ischemic heart disease, allergy for the anesthetics used in this study (propofol/remifentanil).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL22001.018.08 |