To show if there is an increase in reflex time as a function of time after stroke (6 months - 10 years after stroke)
ID
Source
Brief title
Condition
- Central nervous system vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
reflex time measured from force perturbation experiment
reflex time measured from postion perturbation experiment
Secondary outcome
biomechanical parameters:
1. inertia of the hand (g/m2)
2. viscosity/damping (Nms/rad)
3. intrinsic elasticity/stiffness (Nms/rad)
4. velocity-dependent reflex gain (Nms/rad)
Background summary
Aging/degeneration in the neuromuscular system has been operationalised as
reflex time.
Support for this assumption comes from cross-sectional and longitudinal studies
showing an increase in reflex time as a function of increase in age.
Reflex time increases after stroke.
Unpublished reports of experiments with reflex time after stroke, done in the
laboratory of motion analysis in LUMC suggest an additional increase in reflex
time as a function of time after stroke. This effect becomes manifest from
around 24 months after stroke.
Study objective
To show if there is an increase in reflex time as a function of time after
stroke (6 months - 10 years after stroke)
Study design
cross sectional
Study burden and risks
A single measurement session of 1.5 hours including neurological exam and
experiments with a haptic device (robot).
No risks involved.
Albinusdreef 2/Postbus 9600
2300 RC Leiden
Nederland
Albinusdreef 2/Postbus 9600
2300 RC Leiden
Nederland
Listed location countries
Age
Inclusion criteria
1. ischaemic stroke
2. an NIHSS (National Institute of Health Stroke Scale) score of 2 or 3
Exclusion criteria
1. Cognitive disorders which may hamper instruction of the subject.
2. Other neurological, spinal or muscular disorders which can distort the results of the study.
3.Inability to activate the wrist flexors or exert a force with the wrist flexors.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL20098.058.07 |