In the study at hand it is unclear if the VIS-V and the AQ make a differential diagnostic difference between autism and schizofrenia.The objective of this study is to test if the sumscores of the two questionnaires differentiate (significantly, if…
ID
Source
Brief title
Condition
- Developmental disorders NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
To test hypothesis 1 the mean sumscores per instrument, per group will be
calculated for both versions of the VIS-V and the AQ. The mean total scores of
the two groups for both versions of the VIS-V and the AQ will be compared to
each other with T-tests. These tests are used to determine the equality of the
mean scores of the two independent groups.
To test hypothesis 2 the meanscores of the subscales of the VIS-V and the AQ
for both groups will be compared with T-tests. These tests are used to
determine the equality of the mean scores of the two independent groups.
Secondary outcome
To test hypothesis 3 the interference of negative symptomatology with the hight
of the scores on the VIS-V and AQ questionnaire is measured with a liniair
regressionanalysis.
Background summary
It is normally not easy to differentiatie between schizofrenia and autism.
Especially the negative symptoms of schizofrenia make it hard to differentiate
between the two disorders.
Screening instruments in the field of autism for adults are not yet elaborated
enough, to proof their effectiveness between the two disorders. This survey
makes an effort to contribute to this effectiveness. Therefore subject to this
study is to find out to what extend the VIS-V and the AQ will differentiate
between the two disorders.
Study objective
In the study at hand it is unclear if the VIS-V and the AQ make a differential
diagnostic difference between autism and schizofrenia.
The objective of this study is to test if the sumscores of the two
questionnaires differentiate (significantly, if any) between autism and
schizofrenia.
Furthermore with use of the SPQ questionnaire will be analyzed to what extend
the negative symptomatology in the group of schizofrenic participants interfere
with the results of the VIS-V and AQ questionnaire.
We formulate the central question for this study as follows: Does the group
participants with the diagnosis autism has significantly higher scores on the
VIS-V and the AQ then the group participants with the diagnosis schizofrenia
Study design
The central question for this study is leading to the following hypothesis:
1. Individuals with the diagnosis autism has significantly higher scores
(sumscores) on the VIS-V and the AQ then the group participants with the
diagnosis schizofrenia
2. Individuals with the diagnosis autism has significantly higher scores (all
subscales) on the VIS-V and the AQ then the group participants with the
diagnosis schizofrenia
3. The degree of negative symptomatology in the group of schizofrenic
participants, measured by the SPQ, interfere positively with the hight of the
scores on the VIS-V and AQ questionnaire.
Intervention
zie Nederlandse tekst
Study burden and risks
There is a certain timeburden.
The clients with autism will have to fill out two questionnaires (SPQ an
VIS-V), for the AQ and the subtasks of the WAIS were previously done as a
standard diagnostic instrument by the intake of this participants as clients of
the healthcare institute.
The participants will need approximately 40 minutes to fill out the two forms.
The group with schizophrenic participants will be invited twice. The first time
to undergo the Mini-SCAN and to test the oral subtasks of the WAIS III. The
Mini-SCAN takes about 15 minutes. The total interview time of this first
session is about 55 minutes.
During the second session the participants have to fill out three
questionnaires (VIS-V, the AQ and the SPQ). The second session will take about
40 minutes time.
For all participants from both groups (autistic and schizophrenic) their
coaches (casemanagers) from the GGZE will be asked to fill out het
heteroanamnestic version of the VIS-V questionnaire. This will take about 20
minutes time per participant.
Kronehoefstraat 1
5612HK Eindhoven
Nederland
Kronehoefstraat 1
5612HK Eindhoven
Nederland
Listed location countries
Age
Inclusion criteria
- male
- age between 18 and 65
- normal or high verbal intelligence
- diagnosis schizophrenia or high functioning autism
- a comorbid psychiatric desease may not be prominent
Exclusion criteria
see D4a
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL22718.097.08 |