Amount of new fractures in this study population, divided in 4 different groups:group 1 MVF (+) osteoporosis (+)group 2 MVF (+) osteoporosis (-)group 3 MVF (-) osteoporosis (+)group 4 MVF (-) osteoporosis (-) (control group/less risk factors)The…
ID
Source
Brief title
Condition
- Fractures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Incidence of new fractures in this study population.
Secondary outcome
Analyzing the changes of bone mineral density in this population after
treatment or no-treatment and the effect of therapy in patients taking
medication and compliance.
Background summary
Therapy of osteoporosis is started in patients who meet the criteria of the
guideline for treatment of osteoporosis set up by CBO for instance patients
with a bone mineral density (BMD) < - 2,5. But unfortunately a lot of people
with osteopenia (BMD between -1 and -2,5) fracture. Recent research data show
50% of all patients with a non vertebral fracture have a morfometric vertebral
fracture (MVF). A morfometric vertebral fracture is a risk factor for future
fractures in despite of the BMD concluded those authors (Dumitrescu et al).
Systemic follow up of these patients will show new fractures, vertebral and
non vertebral.
Study objective
Amount of new fractures in this study population, divided in 4 different groups:
group 1 MVF (+) osteoporosis (+)
group 2 MVF (+) osteoporosis (-)
group 3 MVF (-) osteoporosis (+)
group 4 MVF (-) osteoporosis (-) (control group/less risk factors)
The secundair aim of this study is to measure the BMD difference and to look at
the therapeutic effects and therapeutic compliance.
Study design
prospective, observational (cohort) study
Study burden and risks
The participants burden is minimalized to one visit to the reumatologist and
previous a DXA scan, X-ray (not all patients), a blood sample and a
questionnaire. This all is considerd to be normal patient care and minimal
burden and risk to the patient.
P. Debyelaan 25; P.O. Box 5800
6202 AZ Maastricht
NL
P. Debyelaan 25; P.O. Box 5800
6202 AZ Maastricht
NL
Listed location countries
Age
Inclusion criteria
women above 50 years
women were included in previous research (Dumitrescu)
Exclusion criteria
male
patients with dementia
patients living abroad
patients with a life expectancy <6 months
patients who are deceased
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL21506.068.08 |