Calculating the incidence of atherosclerosis in patients undergoing a CT-scan of the abdomen for other reasons. Calculating incidence of untreated risk factors for CVD in patients with atherosclerosis on the CT-scan.
ID
Source
Brief title
Condition
- Coronary artery disorders
- Arteriosclerosis, stenosis, vascular insufficiency and necrosis
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Incidence of atherosclerosis in patients undergoing a CT-scan of the abdomen
for other reasons.
Incidence of untreated risk factors in patients with atherosclerosis on the
CT-scan of the abdomen.
Secondary outcome
Incidence of CVD in patients with and without atherosclerosis on CT-scan of the
abdomen.
Relating the number of risk factors to the severity of atherosclerosis on the
CT-scan of the abdomen.
Background summary
Cardiovascular diseases (CVD) are the most important cause of death in the
Netherlands and cause a significant deterioration in quality of life. CVD
starts with atherosclerosis of the arteries. CT-scans of the abdomen can show
signs of atherosclerosis. In current literature few studies can be found that
compare atherosclerosis as a coincidental finding with risk factors for CVD.
Treatment of these risk factors reduces the incidence of CVD significantly.
Study objective
Calculating the incidence of atherosclerosis in patients undergoing a CT-scan
of the abdomen for other reasons. Calculating incidence of untreated risk
factors for CVD in patients with atherosclerosis on the CT-scan.
Study design
Patients are selected by using the criteria stated below. After inclusion and
informed consent the patient will be invited to visit the out-patient clinic of
the Vascular Diseases department. With an interview, a physical examination and
blood analysis a risk profile for CVD will be made. In a second visit these
findings will be shared with the patients.
Study burden and risks
The burden of taking part in this trial consists of visiting the out-patient
clinic of the Vascular Diseases department twice, undergoing venapunction for
blood analysis and collecting a urine sample.
Wagnerlaan 55
6815 AD Arnhem
Nederland
Wagnerlaan 55
6815 AD Arnhem
Nederland
Listed location countries
Age
Inclusion criteria
Age 18-65 years old
Patient has had a CT-scan of the abdomen in the Rijnstate Hospital Arnhem
Patient has given informed consent
Patient has got signs of atherosclerosis on the CT-scan of the abdomen
Exclusion criteria
Indication for making the CT-scan was atherosclerosis or an aneurysm of the large abdominal arteries
Patient has a condition which makes him unable to give informed consent without help of a representative
Patient has a life expectancy shorter than 5 years
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL27362.091.09 |