The main objective is to describe the interactions between physical sensory stimulations and high-level prior assumptions that give rise to visual perception. In our secondary objective, we will advance novel model-based neuroimaging methods by…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Niet van toepassing
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Model parameters of neuronal populations estimated with functional MRI.
Secondary outcome
Not applicable.
Background summary
We infer our visual environment from both physical retinal stimulations and
prior assumptions about the environment. We use a combined behavioural,
computational and human neuroimaging approach to quantify local interactions
between low-level sensory input and high-level prior assumptions that give rise
to visual perception.
Study objective
The main objective is to describe the interactions between physical sensory
stimulations and high-level prior assumptions that give rise to visual
perception. In our secondary objective, we will advance novel model-based
neuroimaging methods by linking it to human neuron properties other than
*activations*, and validate the measurements with predictions derived from
well-established animal neuronal properties.
Study design
Using functional MRI, subjects are scanned on while viewing various visual
stimuli. The first kind of visual stimuli will be used to estimate the
properties of the underlying neuronal population, whereas the second kind of
visual stimuli will validate these models and test hypothesis about these
models.
Study burden and risks
Scanning will take approximately 45-60 min in total per session for each
subject. Functional MRI is a non-invasive technique, so there is no need for
special preparation for the subject. There are no known risks associated with
functional MRI acquisition. The data are used for research purposes only.
However, severe abnormalities may be noticed, in which case a specialist
(radiologist) may be asked for advice, upon decision of the research team. If
the specialist confirms that medical treatment is indicated, then the subject
will be notified. Besides financial remuneration, there are no benefits from
participation in this study for the subjects.
Heidelberglaan 2
3584 CS
Nederland
Heidelberglaan 2
3584 CS
Nederland
Listed location countries
Age
Inclusion criteria
age between 18 and 65
Exclusion criteria
- Ferrous objects in or around the body (e.g. braces, glasses, pacemaker, metal fragments)
- Drug or alcohol abuse over a period of six months prior to the experiment
- History of closed- or open-head injury
- History of neurological illness or endocrinological dysfunction
- Claustrophobia
- Major medical history
- Chronic use of medication
- History of epilepsy
- History of epilepsy in first-degree relatives
- Incapability of giving an informed consent
- pregnancy
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL27591.041.09 |