To demonstrate that externally induced increases in subpalpebral pressure (SPP) relate to clinically significant increases in IOP, and to determine posture dependency of SPP. To determine the effects of protective goggles on SPP under these…
ID
Source
Brief title
Condition
- Glaucoma and ocular hypertension
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
IOP and SPP.
Secondary outcome
NA
Background summary
Glaucoma is the commonest cause of irreversible blindness in the world. An
increased intra-ocular pressure (IOP) is the most important risk-factor for the
development (and progression) of glaucoma. Even without proven increases in IOP
may glaucoma come about or become worse. It is currently unknown how much the
IOP is affected during sleep when the pillow presses against the face and
eyelids. The pressure increases will be measured under the eyelids when
subjects lie horizontally with their heads resting normally on their own
pillows, assuming a posture similar to during sleep.
Study objective
To demonstrate that externally induced increases in subpalpebral pressure (SPP)
relate to clinically significant increases in IOP, and to determine posture
dependency of SPP. To determine the effects of protective goggles on SPP under
these conditions.
Study design
Experimental study.
Intervention
wearing of protective spectacles
Study burden and risks
Participants do not benefit from cooperating. Risks are considered to be small,
the burden is moderate.
Schiedamse Vest 180
3011 BH Rotterdam
Nederland
Schiedamse Vest 180
3011 BH Rotterdam
Nederland
Listed location countries
Age
Inclusion criteria
- Age >18 years.
- Informed consent.
Exclusion criteria
- History of IOP-reducing surgical intervention.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL26971.078.09 |